PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility - Wikidata - awgldk - TriplyDB

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

http://www.wikidata.org/entity/Q24653009

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Human RECQL5 participates in the removal of endogenous DNA damage Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells PARP1 suppresses homologous recombination events in mice in vivo Therapeutic targets of triple-negative breast cancer: a review Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer X-ray repair cross complementing protein 1 in base excision repair.Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy.Poly (ADP-ribose) polymerase inhibitor, an effective radiosensitizer in lung and pancreatic cancers.In vitro functional effects of XPC gene rare variants from bladder cancer patients.PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality.Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells.Targeting poly(ADP-ribose) polymerase activity for cancer therapy.Laser for treatment of aphthous ulcers on bacteria cultures and DNA.Kinetics of endogenous mouse FEN1 in base excision repair.Repair of DNA strand breaks in a minichromosome in vivo: kinetics, modeling, and effects of inhibitors.Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage - when is a DSB not a DSB?Inhibition of DNA damage repair by artificial activation of PARP with siDNA.Disruption of poly(ADP-ribose) homeostasis affects spermiogenesis and sperm chromatin integrity in mice.DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models.53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions Micro-irradiation tools to visualize base excision repair and single-strand break repair Nucleotide excision repair pathway assessment in DNA exposed to low-intensity red and infrared lasers.Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA.Low-intensity red and infrared laser effects at high fluences on Escherichia coli cultures.Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients.The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts.Genetic Evidence for Genotoxic Effect of Entecavir, an Anti-Hepatitis B Virus Nucleotide Analog.Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models.Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair.

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PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

http://www.wikidata.org/entity/Q24653009

description

2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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PARP inhibition versus PARP-1 ...... r and radiation susceptibility

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Camille Godon

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Frédérique Mégnin-Chanet

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Janet Hall

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Nicole Giocanti

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Vincent Favaudon

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P2860

Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon

Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery

The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells

Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway

Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

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4454-4464

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scholarly article

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2836287

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10.1093/NAR/GKN403

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13

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36

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Fabrice P Cordelières

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2008-07-04T00:00:00Z

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5248752

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18603595

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2490739

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