Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells.
about
TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent CellsPARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response.Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways.PARP inhibitors as antitumor agents: a patent update (2013-2015).Tumor Cell Recovery from Senescence Induced by Radiation with PARP Inhibition.Niraparib: First Global Approval.Poly-(ADP-ribose)-polymerase inhibitors as radiosensitizers: a systematic review of pre-clinical and clinical human studies.MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells.Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib.PARP inhibitors as potential therapeutic agents for various cancers: focus on niraparib and its first global approval for maintenance therapy of gynecologic cancers.PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53.
P2860
Q28115068-E34F585C-CA1B-4351-BEC3-632F522D3D72Q36767034-3AD5B2BC-A406-46A9-8418-674967F93102Q36962771-BBA45DAD-D44E-4AFD-8A23-37C6BC7172BDQ38541699-A4ADC4B0-D272-4DED-BC6E-A3BDAFA5358DQ38795712-C63684DE-CEBA-44C7-8F4F-6CCC426CBDA0Q38944795-7BC33737-223D-4E59-9B3A-7F9B960805ACQ39285185-BD3678C3-2C16-4FE0-9A65-211BFE1A2E84Q42083096-913367DF-F2FE-4928-83C1-0ABA31A3D0D9Q42317541-ACFA2861-EEFD-4F1B-B28C-EDBC1D05132DQ47360676-310DF173-1B7A-4569-B675-5B47DDEE5CFEQ48164214-958D5086-27F0-4716-958F-62868BD1CFAEQ51149312-6923AA03-CB36-4515-A21C-EB380BFE8B35
P2860
Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@ast
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@en
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@nl
type
label
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@ast
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@en
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@nl
prefLabel
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@ast
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@en
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Niraparib (MK-4827), a novel p ...... lung and breast cancer cells.
@en
P2093
Carolyn A Buser
Huifeng Liu
Kathleen A Bridges
Raymond E Meyn
Thomas A Buchholz
P2860
P304
P356
10.18632/ONCOTARGET.2083
P407
P577
2014-07-01T00:00:00Z