Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway - Wikidata - awgldk - TriplyDB

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

http://www.wikidata.org/entity/Q24655872

about

Autoinflammatory pustular neutrophilic diseases Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment The Relationship between NALP3 and Autoinflammatory Syndromes Update on Pyrin Functions and Mechanisms of Familial Mediterranean Fever Lighting the fires within: the cell biology of autoinflammatory diseases Autoinflammatory bone diseases Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence The inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome The PYRIN domain in signal transduction Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages.The alphabet of intrinsic disorder: II. Various roles of glutamic acid in ordered and intrinsically disordered proteins.The PCH family member proline-serine-threonine phosphatase-interacting protein 1 targets to the leukocyte uropod and regulates directed cell migration.Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants The PYRIN connection: novel players in innate immunity and inflammation.Pyrin Modulates the Intracellular Distribution of PSTPIP1.Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.Whole genome sequencing identifies missense mutation in MTBP in Shar-Pei affected with Autoinflammatory Disease (SPAID)Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.Monogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: finding the right balance in response to danger signals Alarmins, inflammasomes and immunity.Etiology and management of pyoderma gangrenosum: a comprehensive review.Caspase functions in cell death and disease.When less is more: primary immunodeficiency with an autoinflammatory kick Monogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis.Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes.Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.Th17-biased RORγt transgenic mice become susceptible to a viral model for multiple sclerosis.Inflammasomes and their activation.Interleukin-1 as a common denominator from autoinflammatory to autoimmune disorders: premises, perils, and perspectives Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind An expanding role for interleukin-1 blockade from gout to cancer.The genetics of pyoderma gangrenosum and implications for treatment: a systematic review.Sensors of the innate immune system: their link to rheumatic diseases.Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.The spectrum of autoinflammatory diseases: recent bench to bedside observations

P2860

Q24603182-FEDCB3ED-E30B-40CF-9C94-7651782C2615 Q24631660-9937C79C-BD00-4930-8829-68BB09C04B00 Q24642151-58DBFF3F-6963-481E-8872-351719C9019D Q26749025-C8BFA626-DFA2-4E7F-B9E2-24AF61CFDC57 Q26749573-C2452422-90C3-47A1-912F-949FD5521BD4 Q26827163-468CF205-290A-4EFB-9C0E-A9004EEFF7EF Q26829850-1C519728-3DC5-4938-B688-8E50A1CF78DC Q27011650-22554744-B9BF-40A3-A183-57FD0D9AA2EE Q27325503-4FA76BAE-0F77-4B31-A253-7C07843FCA70 Q28263427-83A626CD-17CA-45E6-AF11-4AB0C04E768D Q28383855-807D9882-422D-42A5-B9C0-0B1ADBBC50E7 Q28396225-26E4A2F9-07F6-4B8C-BB60-6F5F00903510 Q30009552-1F55E391-1EE5-4283-8101-46686BB62310 Q30402098-0D28D4D4-E5D4-46C6-95F4-7DB20F4C7973 Q30482877-DD08658E-C954-4041-95E6-021E2040B509 Q30489231-91FF634E-C416-4A3C-8757-E4DC06134204 Q30956847-074E56AB-35C5-4157-B0A6-935A690639B2 Q33479535-CCACFCE6-203A-465E-860C-756A81B69F03 Q33495569-2C8D6F46-4D28-4DE4-8F53-C6A2D366C67E Q33640755-981806DF-F28E-4ABF-B397-C4D2CD5AF5E0 Q33710807-D8D2FF57-4C5B-4E04-9FB1-9DD528EFA0C5 Q33798590-FE4AD581-3B93-4B5B-95B3-7C3D9F68A51A Q33817302-0704CBCC-1DDC-4FD7-9815-1E5AB64285B7 Q34030811-BD075BD2-A20F-40A5-A41E-5C2ECF808AEE Q34336335-3555B2F4-8DCA-4067-81CF-336C5A184513 Q34420031-05362D1A-DE53-40E3-BFE1-14B8523C14C4 Q34489840-5B606D43-9B3C-4598-84EB-9525E9370E71 Q34506303-D39A9B69-A109-4CE4-8FA7-CC31702A7CFA Q34560380-05203456-8424-49AB-84E6-E5534E6CFB1C Q34608120-E15F98B7-F546-4CAB-BFBB-0FC43399942B Q34622451-1136B74A-A24C-48FF-AAC9-DB335CFA1505 Q34646572-F2C9E582-60FF-48E0-8303-92CA5B06B190 Q34905606-1F7EFD46-BB39-40BF-9B89-E93EE8FAA8BA Q35133812-6612E0B5-0EE2-4B3E-AF5A-4F351E2F5B69 Q35190461-36ED2DC4-CAC4-4EB0-B4E8-C1D8ED12CDE5 Q35219001-9F612107-030A-491C-921E-863411496EB4 Q35371636-F5AE86BE-4874-4F0D-8EB8-AF30D341E639 Q35623130-35B7A01A-9246-44E2-9A54-796341512A9B Q36041225-42713B12-B5FF-4B33-96E9-F88AEF4649B2 Q36048259-A01B6101-2190-4FAA-9919-FA73DD05F1B4

P2860

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

http://www.wikidata.org/entity/Q24655872

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@ast

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@en

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@nl

type

label

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@ast

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@en

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@nl

prefLabel

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@ast

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@en

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@nl

P1433

Q24655872-78568FDC-1D21-4FED-8DC3-6AD4FFF61050

P1476

Q24655872-2D81B4EB-6283-4B25-B4FD-3F5E31900C86

P2093

Q24655872-04B430A0-E100-45DF-BBB5-F23C56F550B0

Q24655872-118D7F31-2DC1-48B2-AEFB-367502C454F8

Q24655872-6A0A5204-6717-42A5-9FAA-BE265B4017DF

Q24655872-A94FC1A4-0367-482B-A479-4459A12C828B

Q24655872-B969B1E2-1A46-4F15-820D-64D1EC397FAB

Q24655872-C9884F14-86D2-405B-A635-20357E62804C

Q24655872-FDCD5F22-846F-4E28-8661-169A9AF177E4

P2860

Q24655872-058460DF-449F-4029-9AEA-6EEA21FF3824

Q24655872-0C8EAF46-5EC5-4033-B270-BB32C64117E8

Q24655872-0CD85700-BA5C-4CA0-B138-6422CE330E91

Q24655872-14CE8205-2679-4DA2-A2C3-F60A378B5C93

Q24655872-2790395D-6250-4552-832E-80C94230A482

Q24655872-3D6BE3EF-7F83-49F2-810D-D4BC6AF604E6

Q24655872-5792D738-7073-4A37-B5C1-8F5AC4FA44D4

Q24655872-66ECFBED-2FAA-438D-921B-27CA2F5189E3

Q24655872-673B8DF7-BAE4-45D5-9D41-AED1DDE6608E

Q24655872-6A77D23B-0388-4893-B674-4345DE07E9A5

P304

Q24655872-62B89ED6-6CA7-4CA8-8EC7-369CABE9B776

P31

Q24655872-1177357E-7A22-4707-9A83-B0541D7D6581

P3181

Q24655872-828B9D87-DBC7-439F-A4DB-7EFF6AC77AD9

P356

Q24655872-1EEF6E44-BF87-4E7D-9C33-8E557505354C

P407

Q24655872-86BB513F-47B0-4EBA-96A9-5F4B66FB1D01

P433

Q24655872-1B623B50-26DB-408A-8C9A-688F36874034

P478

Q24655872-9E1B6290-F272-4254-95CA-4142D0AC722D

P577

Q24655872-346FB2AC-7A55-418E-A764-4A22BE71A380

P5875

Q24655872-EAA42991-C331-4957-9114-A30C4405F770

P698

Q24655872-C22DC836-2E04-4BE3-A6D8-1136D046E9B4

P932

Q24655872-CB4EAA5B-4CAD-4FC7-9F00-67A3902AA83D

P3181

P356

PNAS.2135380100

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Pyrin binds the PSTPIP1/CD2BP1 ...... disorders in the same pathway

@en

P2093

Carol A Wise

http://www.w3.org/2001/XMLSchema#string

Daniel L Kastner

http://www.w3.org/2001/XMLSchema#string

Elizabeth Mansfield

http://www.w3.org/2001/XMLSchema#string

Geryl Wood

http://www.w3.org/2001/XMLSchema#string

Keith M Hull

http://www.w3.org/2001/XMLSchema#string

Michael Centola

http://www.w3.org/2001/XMLSchema#string

Nitza G Shoham

http://www.w3.org/2001/XMLSchema#string

P2860

A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.

ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton

Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein

P304

13501-6

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1648930

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.2135380100

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

100

http://www.w3.org/2001/XMLSchema#string

P577

2003-11-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

9028878

http://www.w3.org/2001/XMLSchema#string

P698

14595024

http://www.w3.org/2001/XMLSchema#string

P932

263843

http://www.w3.org/2001/XMLSchema#string