Targeting protein serine/threonine phosphatases for drug development
about
Phosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of ParkinsonismIdentification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycleCounteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasVirulence-Associated Enzymes of Cryptococcus neoformansTGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyA unique Kelch domain phosphatase in Plasmodium regulates ookinete morphology, motility and invasionDevelopment of a Peptide that Selectively Activates Protein Phosphatase-1 in Living CellsThe quest for an effective and safe personalized cell therapy using epigenetic toolsThe Basic Biology of PP2A in Hematologic Cells and MalignanciesMass spectrometric detection and characterization of atypical membrane-bound zinc-sensitive phosphatases modulating GABAA receptorsSelectivity and potency of microcystin congeners against OATP1B1 and OATP1B3 expressing cancer cellsPhosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based AssaysMorphologic, Phylogenetic and Chemical Characterization of a Brackish Colonial Picocyanobacterium (Coelosphaeriaceae) with Bioactive PropertiesAn ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmissionInvestigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.Conformational isomers of calcineurin follow distinct dissociation pathways.Total synthesis and evaluation of phostriecin and key structural analoguesMathematical modelling of the MAP kinase pathway using proteomic datasetsInAKTivation of insulin/IGF-1 signaling by dephosphorylation.Microcystin-LR (MCLR) induces a compensation of PP2A activity mediated by α4 protein in HEK293 cells.Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog.The extended PP1 toolkit: designed to create specificity.Determinants for Substrate Specificity of Protein Phosphatase 2A.Viewing serine/threonine protein phosphatases through the eyes of drug designersBisphenol-A affects male fertility via fertility-related proteins in spermatozoa.Aspects of eukaryotic-like signaling in Gram-positive cocci: a focus on virulence.Adaptation of HepG2 cells to a steady-state reduction in the content of protein phosphatase 6 (PP6) catalytic subunitWip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xL ratioEfficient PKC inhibitor screening achieved using a quantitative CE-LIF assay.Label-free electrochemical impedance detection of kinase and phosphatase activities using carbon nanofiber nanoelectrode arrays.Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response.Self-association of okadaic acid: structural and pharmacological significanceNovel Ser/Thr protein phosphatases in cell death regulationSystemic Inhibition of CREB is Well-tolerated in vivo.Prostate cancer: the need for biomarkers and new therapeutic targets.The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.Global analysis of serine/threonine and tyrosine protein phosphatase catalytic subunit genes in Neurospora crassa reveals interplay between phosphatases and the p38 mitogen-activated protein kinase.Bacterial serine/threonine protein kinases in host-pathogen interactions.
P2860
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P2860
Targeting protein serine/threonine phosphatases for drug development
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Targeting protein serine/threonine phosphatases for drug development
@ast
Targeting protein serine/threonine phosphatases for drug development
@en
Targeting protein serine/threonine phosphatases for drug development
@nl
type
label
Targeting protein serine/threonine phosphatases for drug development
@ast
Targeting protein serine/threonine phosphatases for drug development
@en
Targeting protein serine/threonine phosphatases for drug development
@nl
prefLabel
Targeting protein serine/threonine phosphatases for drug development
@ast
Targeting protein serine/threonine phosphatases for drug development
@en
Targeting protein serine/threonine phosphatases for drug development
@nl
P2860
P3181
P356
P1476
Targeting protein serine/threonine phosphatases for drug development
@en
P2093
Brian E Wadzinski
Jamie L McConnell
P2860
P304
P3181
P356
10.1124/MOL.108.053140
P407
P577
2009-06-01T00:00:00Z