Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
about
Widespread presence of "bacterial-like" PPP phosphatases in eukaryotesA protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2AInhibition of calcineurin phosphatase activity by a calcineurin B homologous proteinCalcineurin homologous protein as an essential cofactor for Na+/H+ exchangersConstitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescenceIdentification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration CCrystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexesCrystal structure of human calcineurin complexed with cyclosporin A and human cyclophilinCrystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolutionTargeting protein serine/threonine phosphatases for drug developmentThe human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptideStructural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactionsPost-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomicsAn Overview of Predictors for Intrinsically Disordered Proteins over 2010-2014Calcineurin inhibition and new-onset diabetes mellitus after transplantationSyndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathwaySolution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamicsCrystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1The crystal structure of the novel calcium-binding protein AtCBL2 from Arabidopsis thalianaDesign and structure-based study of new potential FKBP12 inhibitorsThe structure of the C-terminal domain of the protein kinase AtSOS2 bound to the calcium sensor AtSOS3.Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal CoordinatesStructural basis for regulation of protein phosphatase 1 by inhibitor-2Metal active site elasticity linked to activation of homocysteine in methionine synthasesSubstrate-Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenesSolution structure of the inhibitory phosphorylation domain of myosin phosphatase targeting subunit 1NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of CalcineurinSolution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulinStructure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomidevSDC: a method to improve early recognition in virtual screening when limited experimental resources are availableDistinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination.Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosisFKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domainStructural basis of protein phosphatase 1 regulationTuning of a neuronal calcium sensorAKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding regionAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionThe immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target proteinCalculation of the Absolute Free Energy of Binding and Related Entropies with the HSMD-TI Method: The FKBP12-L8 Complex
P2860
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P2860
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@ast
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en-gb
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@nl
type
label
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@ast
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en-gb
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@nl
prefLabel
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@ast
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en-gb
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@nl
P2093
P3181
P356
P1433
P1476
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
@en
P2093
A Tempczyk
C R Kissinger
D R Knighton
E W Moomaw
K D Tucker
L A Pelletier
R E Showalter
V J Kalish
P2888
P3181
P356
10.1038/378641A0
P407
P577
1995-12-07T00:00:00Z
P6179
1018812919