Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted

Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted

Item
http://www.wikidata.org/entity/Q24658050
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfurationFolate MetabolismDietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice.High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolismEvidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohortFolate and vitamin B12 in idiopathic male infertility.Plasma choline metabolites associate with metabolic stress among young overweight men in a genotype-specific manner.Choline metabolites: gene by diet interactions.Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis.Nutrition in pregnancy: the argument for including a source of choline.Common Genetic Variants Alter Metabolism and Influence Dietary Choline Requirements.Dietary Reference Values for cholineCommon Polymorphisms That Affect Folate Transport or Metabolism Modify the Effect of the MTHFR 677C > T Polymorphism on Folate Status.Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C.Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro.
P2860

Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted

Item
http://www.wikidata.org/entity/Q24658050
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Genetic variants in phosphatid ...... en folate intake is restricted
@ast
Genetic variants in phosphatid ...... en folate intake is restricted
@en
Genetic variants in phosphatid ...... en folate intake is restricted
@nl
type
label
Genetic variants in phosphatid ...... en folate intake is restricted
@ast
Genetic variants in phosphatid ...... en folate intake is restricted
@en
Genetic variants in phosphatid ...... en folate intake is restricted
@nl
prefLabel
Genetic variants in phosphatid ...... en folate intake is restricted
@ast
Genetic variants in phosphatid ...... en folate intake is restricted
@en
Genetic variants in phosphatid ...... en folate intake is restricted
@nl
P1433
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P1433
P1476
Genetic variants in phosphatid ...... en folate intake is restricted
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P2093
P2860
P304
P31
P356
10.1016/J.JADA.2008.10.046
P407
P433
P478
P577
P5875
P698
P921
P932