The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading
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Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeletonSyndecan-regulated receptor signalingThe cysteine-rich domain regulates ADAM protease function in vivo.ADAM 12 protease induces adipogenesis in transgenic miceSyndecans in tumor cell adhesion and signalingADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural OverviewHeparan Sulfate Proteoglycans May Promote or Inhibit Cancer Progression by Interacting with Integrins and Affecting Cell MigrationSyndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and PrognosticationA unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilizationMelanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagenDirect interaction between the cytoplasmic tail of ADAM 12 and the Src homology 3 domain of p85alpha activates phosphatidylinositol 3-kinase in C2C12 cellsLocalization of the transmembrane proteoglycan syndecan-4 and its regulatory kinases in costameres of rat cardiomyocytes: a deconvolution microscopic studyThe splicing and fate of ADAM33 transcripts in primary human airways fibroblastsMice with a targeted deletion of the tetranectin gene exhibit a spinal deformityPositive selection neighboring functionally essential sites and disease-implicated regions of mammalian reproductive proteinsMetalloprotease-disintegrin ADAM 12 binds to the SH3 domain of Src and activates Src tyrosine kinase in C2C12 cells.ADAM13 disintegrin and cysteine-rich domains bind to the second heparin-binding domain of fibronectin.A disintegrin and metalloproteinase-12 (ADAM12): function, roles in disease progression, and clinical implicationsConservation and divergence of ADAM family proteins in the Xenopus genome.Meltrin beta mini, a new ADAM19 isoform lacking metalloprotease and disintegrin domains, induces morphological changes in neuronal cells.RACK1, a new ADAM12 interacting protein. Contribution to liver fibrogenesis.A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cellsADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation.ADAM12 and ADAM17 gene expression in laser-capture microdissected and non-microdissected breast tumors.ADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis.The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry.Intracellular processing of metalloprotease disintegrin ADAM12.Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration.Variability in melanoma metalloproteinase expression profilingMice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.Phenotypic analysis of Meltrin alpha (ADAM12)-deficient mice: involvement of Meltrin alpha in adipogenesis and myogenesisCrystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffoldMetzincin proteases and their inhibitors: foes or friends in nervous system physiology?Physiology and pathophysiology of matrix metalloproteases.ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factorExtracellular proteases as targets for drug developmentPotential role for ADAM15 in pathological neovascularization in mice.ADAM33: a novel therapeutic target for asthma.ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
P2860
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P2860
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@ast
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@en
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@nl
type
label
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@ast
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@en
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@nl
prefLabel
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@ast
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@en
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@nl
P2093
P2860
P3181
P356
P1476
The cysteine-rich domain of hu ...... egrin-dependent cell spreading
@en
P2093
A Zolkiewska
C Brakebusch
C Fröhlich
J K Langford
K Ishiguro
R D Sanderson
P2860
P304
P3181
P356
10.1083/JCB.149.5.1143
P407
P577
2000-05-29T00:00:00Z