ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor - Wikidata - awgldk - TriplyDB

ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor

ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor

http://www.wikidata.org/entity/Q35103401

about

Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis ADAM28 is overexpressed in human non-small cell lung carcinomas and correlates with cell proliferation and lymph node metastasis Structural and functional impact of cancer-related missense somatic mutations.ADAM-12 as a diagnostic marker for the proliferation, migration and invasion in patients with small cell lung cancer.RACK1, a new ADAM12 interacting protein. Contribution to liver fibrogenesis.Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor Therapeutic strategies for inhibiting invasion in glioblastoma.ADAM12 and ADAM17 gene expression in laser-capture microdissected and non-microdissected breast tumors.The role of SnoN in transforming growth factor beta1-induced expression of metalloprotease-disintegrin ADAM12.Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion.Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function.Z-DNA-forming silencer in the first exon regulates human ADAM-12 gene expression.N-glycosylation regulates ADAM8 processing and activation Metzincin proteases and their inhibitors: foes or friends in nervous system physiology?Role of A disintegrin and metalloprotease-12 in neutrophil recruitment induced by airway epithelium.Alternative mRNA splicing generates two distinct ADAM12 prodomain variants.ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.Expression of a-disintegrin and metalloproteinase 10 correlates with grade of malignancy in human glioma.The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.ADAM-9 is a novel mediator of tenascin-C-stimulated invasiveness of brain tumor-initiating cells.A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion ADAM12 induces estrogen-independence in breast cancer cells.The role of proteases in regulating Eph/ephrin signaling.ADAM proteases, ErbB pathways and cancer.Tissue fibrosis and carcinogenesis: divergent or successive pathways dictate multiple molecular therapeutic targets for oligo decoy therapies.(Make) stick and cut loose--disintegrin metalloproteases in development and disease.ADAMs, cell migration and cancer.miR-135b suppresses tumorigenesis in glioblastoma stem-like cells impairing proliferation, migration and self-renewal.Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.Inhibition of angiogenesis and invasion in malignant gliomas.Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.ADAM9 Expression Is Associate with Glioma Tumor Grade and Histological Type, and Acts as a Prognostic Factor in Lower-Grade Gliomas Differential gene expression analysis of subcutaneous fat, fascia, and skin overlying a Dupuytren's disease nodule in comparison to control tissue.p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.The EGFR-HER2 module: a stem cell approach to understanding a prime target and driver of solid tumors.Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.Upregulation of ADAM12 contributes to accelerated cell proliferation and cell adhesion-mediated drug resistance (CAM-DR) in Non-Hodgkin's Lymphoma.ADAM12 is a prognostic factor associated with an aggressive molecular subtype of high-grade serous ovarian carcinoma.

P2860

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P2860

ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor

http://www.wikidata.org/entity/Q35103401

description

2004 nî lūn-bûn

@nan

2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@ast

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@en

type

label

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@ast

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@en

prefLabel

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@ast

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@en

P1433

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P356

S0002-9440(10)63429-3

P1433

The American Journal of Pathology

P1476

ADAM12 is selectively overexpr ...... inding epidermal growth factor

@en

P2093

Aiko Okada

http://www.w3.org/2001/XMLSchema#string

Eiji Ikeda

http://www.w3.org/2001/XMLSchema#string

Eiko Ohuchi

http://www.w3.org/2001/XMLSchema#string

Kazunari Yoshida

http://www.w3.org/2001/XMLSchema#string

Masayuki Shimoda

http://www.w3.org/2001/XMLSchema#string

Mitsutoshi Nakada

http://www.w3.org/2001/XMLSchema#string

Takahide Kodama

http://www.w3.org/2001/XMLSchema#string

Takashi Ohtsuka

http://www.w3.org/2001/XMLSchema#string

Takayuki Shiomi

http://www.w3.org/2001/XMLSchema#string

Yasunori Okada

http://www.w3.org/2001/XMLSchema#string

P2860

A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo

A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3

Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS

Roles of Meltrin beta /ADAM19 in the processing of neuregulin

Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia

Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site

P304

1743-1753

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scholarly article

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10.1016/S0002-9440(10)63429-3

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5

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165

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8206804

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15509542

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1618672

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