DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction
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Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymeraseThe selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic dosesStable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectorsIncreased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 MiceImmunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged MiceHuman papillomavirus type 16 E7 DNA vaccine: mutation in the open reading frame of E7 enhances specific cytotoxic T-lymphocyte induction and antitumor activity.DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination.Suppression of murine cytomegalovirus (MCMV) replication with a DNA vaccine encoding MCMV M84 (a homolog of human cytomegalovirus pp65)Identification of immunodominant and conformational epitopes in the capsid protein of hepatitis E virus by using monoclonal antibodiesPapillomavirus pseudovirus: a novel vaccine to induce mucosal and systemic cytotoxic T-lymphocyte responses.Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences.DNA vaccination against tuberculosis: expression of a ubiquitin-conjugated tuberculosis protein enhances antimycobacterial immunity.DNA vaccine combinations expressing either tissue plasminogen activator signal sequence fusion proteins or ubiquitin-conjugated antigens induce sustained protective immunity in a mouse model of pulmonary tuberculosisUbiquitin-fused and/or multiple early genes from cottontail rabbit papillomavirus as DNA vaccines.Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines.DNA vaccination partially protects against African swine fever virus lethal challenge in the absence of antibodies.Just one position-independent lysine residue can direct MelanA into proteasomal degradation following N-terminal fusion of ubiquitin.Expression library immunization can confer protection against lethal challenge with African swine fever virusStrong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challengeFusion of ubiquitin to HIV gag impairs human monocyte-derived dendritic cell maturation and reduces ability to induce gag T cell responses.Co-expression of ubiquitin gene and capsid protein gene enhances the potency of DNA immunization of PCV2 in miceTranscription factor Fos-related antigen 1 is an effective target for a breast cancer vaccine.Optimization of a gene electrotransfer procedure for efficient intradermal immunization with an hTERT-based DNA vaccine in miceDesign and evaluation of optimized artificial HIV-1 poly-T cell-epitope immunogensA highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge.The signal peptide sequence impacts the immune response elicited by a DNA epitope vaccine.Immunogenicity evaluation of a rationally designed polytope construct encoding HLA-A*0201 restricted epitopes derived from Leishmania major related proteins in HLA-A2/DR1 transgenic mice: steps toward polytope vaccineThe ubiquitination of the influenza A virus PB1-F2 protein is crucial for its biological functionUbiquitin conjugation of hepatitis B virus core antigen DNA vaccine leads to enhanced cell-mediated immune response in BALB/c mice.The immune response to a vesicular stomatitis virus vaccine vector is independent of particulate antigen secretion and protein turnover rate.Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cellsCross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines.Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency.DNA vaccination protects mice against challenge with Listeria monocytogenes expressing the hepatitis C virus NS3 protein.Proteomic contributions to our understanding of vaccine and immune responses.An autologous oral DNA vaccine protects against murine melanoma.Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis.Protective immunity with an E1 multivalent epitope DNA vaccine against cottontail rabbit papillomavirus (CRPV) infection in an HLA-A2.1 transgenic rabbit modelCodon optimization of the tat antigen of human immunodeficiency virus type 1 generates strong immune responses in mice following genetic immunization.DNA vaccination: using the patient's immune system to overcome cancer
P2860
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P2860
DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@ast
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@en
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@nl
type
label
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@ast
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@en
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@nl
prefLabel
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@ast
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@en
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@nl
P2093
P2860
P921
P1433
P1476
DNA immunization: ubiquitinati ...... t abrogates antibody induction
@en
P2093
P2860
P304
P407
P577
1997-11-01T00:00:00Z