Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome
about
Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal sizeEfficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis.Update on human herpesvirus 6 biology, clinical features, and therapyRoles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombinationSite-specific integration of adeno-associated virus involves partial duplication of the target locus.Adeno-associated virus site-specifically integrates into a muscle-specific DNA regionDesigner gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transferGenomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase.DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.AAV-iRFP labelling of human mesenchymal stem cells for near-infrared fluorescence imagingDevelopment of animal models for adeno-associated virus site-specific integration.Adeno-associated virus vectors and hematologySite-specific integration of adeno-associated virus into an episome with the target locus via a deletion-substitution mechanismConditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Kinetics of recombinant adeno-associated virus-mediated gene transfer.Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification.Amino-terminal domain exchange redirects origin-specific interactions of adeno-associated virus rep78 in vitro.Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat.A genetic screen identifies a cellular regulator of adeno-associated virus.Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applicationsFormation of AAV single stranded DNA genome from a circular plasmid in Saccharomyces cerevisiaeSubstitution of adeno-associated virus Rep protein binding and nicking sites with human chromosome 19 sequences.A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19.Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.Herpes simplex virus type 1/adeno-associated virus hybrid vectors mediate site-specific integration at the adeno-associated virus preintegration site, AAVS1, on human chromosome 19.Detection of antibodies directed against human herpesvirus 6 U94/REP in sera of patients affected by multiple sclerosis.Adeno-associated virus: a key to the human genome?Spatial and temporal organization of adeno-associated virus DNA replication in live cells.Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector.Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector.Identification of an insulator in AAVS1, a preferred region for integration of adeno-associated virus DNA.p53 inhibits adeno-associated viral vector integrationThe amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerizationPreferential integration of adeno-associated virus type 2 into a polypyrimidine/polypurine-rich region within AAVS1.Targeting site-specific chromosome integration.Adeno-associated virus vectors: potential applications for cancer gene therapy.Cell- and gene-based therapeutic strategies for periodontal regenerative medicine.Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation
P2860
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P2860
Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Adeno-associated virus Rep pro ...... ique locus in the human genome
@ast
Adeno-associated virus Rep pro ...... ique locus in the human genome
@en
Adeno-associated virus Rep pro ...... ique locus in the human genome
@nl
type
label
Adeno-associated virus Rep pro ...... ique locus in the human genome
@ast
Adeno-associated virus Rep pro ...... ique locus in the human genome
@en
Adeno-associated virus Rep pro ...... ique locus in the human genome
@nl
prefLabel
Adeno-associated virus Rep pro ...... ique locus in the human genome
@ast
Adeno-associated virus Rep pro ...... ique locus in the human genome
@en
Adeno-associated virus Rep pro ...... ique locus in the human genome
@nl
P2093
P2860
P1433
P1476
Adeno-associated virus Rep pro ...... ique locus in the human genome
@en
P2093
G J Kurtzman
G Natsoulis
R T Surosky
S A McQuiston
S G Godwin
P2860
P304
P407
P577
1997-10-01T00:00:00Z