Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.

Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.

Item
http://www.wikidata.org/entity/Q33794816
Gene Therapy for Cardiovascular DiseaseTargeted chromosomal insertion of large DNA into the human genome by a fiber-modified high-capacity adenovirus-based vector system.Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat.Vectors for the treatment of autoimmune disease.Preferential integration of adeno-associated virus type 2 into a polypyrimidine/polypurine-rich region within AAVS1.Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.Regulated gene insertion by steroid-induced PhiC31 integrase.Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease.Selective cleavage of AAVS1 substrates by the adeno-associated virus type 2 rep68 protein is dependent on topological and sequence constraints.Characteristics of the adeno-associated virus preintegration site in human chromosome 19: open chromatin conformation and transcription-competent environment.Integration of adeno-associated virus 2 DNA in human MKR melanoma cells induces a peptide with oncosuppressive properties.A method mediated AAVS1 recombination with Rep mRNA and homologous arms.
P2860

Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.

Item
http://www.wikidata.org/entity/Q33794816
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Conditional site-specific inte ...... -associated virus/Rep protein.
@ast
Conditional site-specific inte ...... -associated virus/Rep protein.
@en
type
label
Conditional site-specific inte ...... -associated virus/Rep protein.
@ast
Conditional site-specific inte ...... -associated virus/Rep protein.
@en
prefLabel
Conditional site-specific inte ...... -associated virus/Rep protein.
@ast
Conditional site-specific inte ...... -associated virus/Rep protein.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
Conditional site-specific inte ...... -associated virus/Rep protein.
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.74.1.281-294.2000
P433
P478
P577
P698
P932