Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
about
NMDA receptor modulators: an updated patent review (2013-2014)Glutamate receptor ion channels: structure, regulation, and functionPharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesiaAntagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of DiabetesNR2B Antagonist CP-101,606 Abolishes Pitch-Mediated Deviance Detection in Awake Rats.Synaptic GluN2A and GluN2B containing NMDA receptors within the superficial dorsal horn activated following primary afferent stimulation.Peripheral N-methyl-d-aspartate receptors contribute to mechanical hypersensitivity in a rat model of inflammatory temporomandibular joint pain.Arthritis and pain. Future targets to control osteoarthritis painIntracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root.Discovery of 3-substituted aminocyclopentanes as potent and orally bioavailable NR2B subtype-selective NMDA antagonists.Paeoniflorin inhibits excitatory amino acid agonist-and high-dose morphine-induced nociceptive behavior in mice via modulation of N-methyl-D-aspartate receptors.Role of altered structure and function of NMDA receptors in development of alcohol dependence.Differential Effects of an NR2B NAM and Ketamine on Synaptic Potentiation and Gamma Synchrony: Relevance to Rapid-Onset Antidepressant Efficacy.Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersFunctional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons.NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins.Receptor and channel heteromers as pain targets.NR2B receptor blockade inhibits pain-related sensitization of amygdala neuronsAllosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potentialTargeting Opioid-Induced Hyperalgesia in Clinical Treatment: Neurobiological Considerations.The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain.Ion channels involved in stroke.Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain.The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice.Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC.An electronic pressure-meter nociception paw test for mice.Glutamate and tachykinin receptors in central sensitization of withdrawal reflexes in the decerebrated rabbit.Brain but not spinal NR2B receptor is responsible for the anti-allodynic effect of an NR2B subunit-selective antagonist CP-101,606 in a rat chronic constriction injury model.An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models.The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.Why not ketamine?
P2860
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P2860
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@ast
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@en
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@nl
type
label
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@ast
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@en
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@nl
prefLabel
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@ast
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@en
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@nl
P2093
P3181
P356
P1476
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist
@en
P2093
A Nagahisa
F S Menniti
K Taniguchi
M Mizutani
T Ishikawa
P304
P3181
P356
10.1038/SJ.BJP.0701445
P407
P577
1997-11-01T00:00:00Z