Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers
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Intermediate phenotypes and biomarkers of treatment outcome in major depressive disorderAntioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of DesminopathyDevelopment of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.The effect of bromine scanning around the phenyl group of 4-phenylquinolone derivatives.Progress in the Development of Small Molecule Therapeutics for the Treatment of Neuronal Ceroid Lipofuscinoses (NCLs).P90RSK and Nrf2 Activation via MEK1/2-ERK1/2 Pathways Mediated by Notoginsenoside R2 to Prevent 6-Hydroxydopamine-Induced Apoptotic Death in SH-SY5Y Cells.Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's diseaseQuantitative Electroencephalographic Biomarkers in Preclinical and Human Studies of Huntington's Disease: Are They Fit-for-Purpose for Treatment Development?Rational drug discovery design approaches for treating Parkinson's disease.Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol.Binding of ArgTX-636 in the NMDA receptor ion channelTranscriptional targeting of sphingosine-1-phosphate receptor S1P2 by epigallocatechin-3-gallate prevents sphingosine-1-phosphate-mediated signaling in macrophage-differentiated HL-60 promyelomonocytic leukemia cells.Targeted Antioxidant, Catalase-SKL, Reduces Beta-Amyloid Toxicity in the Rat Brain.Nitric Oxide as a Switching Mechanism between Axon Degeneration and Regrowth during Developmental Remodeling.Inhibitory effects of NAMI-A-like ruthenium complexes on prion neuropeptide fibril formation.Preventive and therapeutic potential of ascorbic acid in neurodegenerative diseases.Computer-assisted designed "selenoxy-chinolin": a new catalytic mechanism of the GPx-like cycle and inhibition of metal-free and metal-associated Aβ aggregation.Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2).Impact of novel N-aryl piperamide NO donors on NF-κB translocation in neuroinflammation: rational drug-designing synthesis and biological evaluation.6-Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model.Design, synthesis and evaluation of seleno-dihydropyrimidinones as potential multi-targeted therapeutics for Alzheimer's disease.Crystal structure of ethyl 4-[4-(di-methyl-amino)-phen-yl]-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexa-hydro-quinoline-3-carboxyl-ateNeuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
P2860
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P2860
Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Target- and mechanism-based th ...... diseases: strength in numbers
@ast
Target- and mechanism-based th ...... diseases: strength in numbers
@en
type
label
Target- and mechanism-based th ...... diseases: strength in numbers
@ast
Target- and mechanism-based th ...... diseases: strength in numbers
@en
prefLabel
Target- and mechanism-based th ...... diseases: strength in numbers
@ast
Target- and mechanism-based th ...... diseases: strength in numbers
@en
P2093
P2860
P356
P1476
Target- and mechanism-based th ...... diseases: strength in numbers
@en
P2093
Dustin D Hawker
Jan J Mataka
Kristin Jansen Labby
Paul C Trippier
Richard B Silverman
P2860
P304
P356
10.1021/JM3015926
P407
P577
2013-03-27T00:00:00Z