Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing - Wikidata - awgldk - TriplyDB

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

http://www.wikidata.org/entity/Q24672994

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The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin Processing of microRNA primary transcripts requires heme in mammalian cells Crystal structure of human DGCR8 core MicroRNA aberrations: An emerging field for gallbladder cancer management RNA Binding Proteins in the miRNA Pathway MicroRNA Biomarkers for Coronary Artery Disease?Micromanaging abdominal aortic aneurysms Epigenetics and psychostimulant addiction Ribonuclease III mechanisms of double-stranded RNA cleavage Genetic variants in microRNA genes: impact on microRNA expression, function, and disease The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species.Solution structure of the Drosha double-stranded RNA-binding domain Structure of the dimerization domain of DiGeorge Critical Region 8 Experimental procedures to identify and validate specific mRNA targets of miRNAs miRNA Repertoires of Demosponges Stylissa carteri and Xestospongia testudinaria The Microprocessor controls the activity of mammalian retrotransposons Many roads to maturity: microRNA biogenesis pathways and their regulation Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross Evolution of MIR168 paralogs in Brassicaceae.DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.Gene silencing by RNA interference in Sarcoptes scabiei: a molecular tool to identify novel therapeutic targets.Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery.DGCR8 recognizes primary transcripts of microRNAs through highly cooperative binding and formation of higher-order structures.Regulation of human Dicer by the resident ER membrane protein CLIMP-63 Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing.miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization.Exercise: putting action into our epigenome.The role of human Dicer-dsRBD in processing small regulatory RNAs Genome wide screening of RNAi factors of Sf21 cells reveal several novel pathway associated proteins Functional association of the Microprocessor complex with the spliceosome.Cellular localization and processing of primary transcripts of exonic microRNAs.Differential expression of microRNAs in ischemic heart disease.Identification of microRNAs in the coral Stylophora pistillata MicroRNAs: new players in IBD.Selective microRNA-Offset RNA expression in human embryonic stem cells A microRNA profile of human CD8(+) regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes.Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8 SmD1 Modulates the miRNA Pathway Independently of Its Pre-mRNA Splicing Function.Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples.The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage.

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Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

http://www.wikidata.org/entity/Q24672994

description

2006 nî lūn-bûn

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2006 թուականին հրատարակուած գիտական յօդուած

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2006 թվականին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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prefLabel

Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Characterization of DGCR8/Pash ...... ha in primary miRNA processing

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Nucleic Acids Research

P1476

Characterization of DGCR8/Pash ...... ha in primary miRNA processing

@en

P2093

Jinju Han

http://www.w3.org/2001/XMLSchema#string

Kyu-Hyeon Yeom

http://www.w3.org/2001/XMLSchema#string

Mi Ra Suh

http://www.w3.org/2001/XMLSchema#string

V Narry Kim

http://www.w3.org/2001/XMLSchema#string

Yoontae Lee

http://www.w3.org/2001/XMLSchema#string

P2860

The nuclear RNase III Drosha initiates microRNA processing

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

The Microprocessor complex mediates the genesis of microRNAs

The Drosha-DGCR8 complex in primary microRNA processing

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

MicroRNA maturation: stepwise processing and subcellular localization.

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

MicroRNA genes are transcribed by RNA polymerase II

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4622-9

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scholarly article

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1565215

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10.1093/NAR/GKL458

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16

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34

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2006-01-01T00:00:00Z

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6826448

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P698

16963499

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P921

microprocessor complex

P932

1636349

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