Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire - Wikidata - awgldk - TriplyDB

Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire

Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire

http://www.wikidata.org/entity/Q24673005

about

ZAP-70 restoration in mice by in vivo thymic electroporation RNA Relics and Origin of Life IMGT/GeneInfo: T cell receptor gamma TRG and delta TRD genes in database give access to all TR potential V(D)J recombinations.Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locus Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection.Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains.Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination.Highly diverse TCRα chain repertoire of pre-immune CD8⁺ T cells reveals new insights in gene recombination.An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells Optimal epitope composition after antigen screening using a live bacterial delivery vector: application to TRP-2.IMGT/GeneInfo: enhancing V(D)J recombination database accessibility PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer.Clonal restriction and predominance of regulatory T cells in coronary thrombi of patients with acute coronary syndromes.Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus.Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients.A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires A new high-throughput sequencing method for determining diversity and similarity of T cell receptor (TCR) α and β repertoires and identifying potential new invariant TCR α chains Thymocytes may persist and differentiate without any input from bone marrow progenitors Prospects for a T-cell receptor vaccination against myasthenia gravis.Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene.Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure Does the developmental status of Valpha14i NKT cells play a role in disease?Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells.Uneven colonization of the lymphoid periphery by T cells that undergo early TCR{alpha} rearrangements.The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis.CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival The immune system as a self-centered network of lymphocytes.Development of autologous cytotoxic CD4+ T clones in a human model of B-cell non-Hodgkin follicular lymphoma.Tcrd Rearrangement Redirects a Processive Tcra Recombination Program to Expand the Tcra Repertoire.Equal opportunity for all.Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice.Half of the T-cell repertoire combinatorial diversity is genetically determined in humans and humanized mice.

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Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire

http://www.wikidata.org/entity/Q24673005

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2002 nî lūn-bûn

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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2002年の論文

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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Journal of Experimental Medicine

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Quantitative and qualitative c ...... eceptor alpha chain repertoire

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P2093

Catherine Aude-Garcia

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Evelyne Jouvin-Marche

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Florence Thuderoz

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Jacques Demongeot

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Maighréad Gallagher

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Mélanie Loiodice

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Nicolas Pasqual

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Patrice Noël Marche

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Rod Ceredig

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P2860

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement

Pleiotropic changes controlled by the pre-T-cell receptor.

Comparative genomics of the human and mouse T cell receptor loci.

The human immunoglobulin VH repertoire.

Regulation of TCR alpha and beta gene allelic exclusion during T-cell development.

The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability.

V(D)J recombination: molecular biology and regulation.

Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

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1163-73

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scholarly article

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3042502

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10.1084/JEM.20021074

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9

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196

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2002-11-04T00:00:00Z

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11047567

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12417627

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2194109

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