An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
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Antitumor Responses of Invariant Natural Killer T CellsT cell metabolism drives immunityβ-catenin/TCF-1 pathway in T cell development and differentiationHEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticityStages versus subsets: Invariant Natural Killer T cell lineage differentiationThe establishment of B versus T cell identityCritical roles of RasGRP1 for invariant NKT cell developmentIL-15 regulates homeostasis and terminal maturation of NKT cellsMetabolic regulator Fnip1 is crucial for iNKT lymphocyte development.The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.ID'ing innate and innate-like lymphoid cellsTranscriptional control of invariant NKT cell development.Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiencyDiverse roles of inhibitor of differentiation 2 in adaptive immunity.T cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor α-chain rearrangement required for NKT cell developmentEpigenetic reduction in invariant NKT cells following in utero vitamin D deficiency in mice.The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development.The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor.Making memory at birth: understanding the differentiation of natural killer T cellsCell-autonomous requirement for TCF1 and LEF1 in the development of Natural Killer T cells.ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells.The transcriptional repressor NKAP is required for the development of iNKT cellsCXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylationThe microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis.Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets.Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansionThe transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.Transcriptional regulation of NKT cell development and homeostasis.Type I natural killer T cells: naturally born for fighting.Control of early stages in invariant natural killer T-cell development.Transcription factor network regulating CD(+)CD8(+) thymocyte survival.Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.Orchestration of invariant natural killer T cell development by E and Id proteins.The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.Cytokines, Transcription Factors, and the Initiation of T-Cell Development.Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells.Id2 regulates hyporesponsive invariant natural killer T cells.E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.
P2860
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P2860
An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An essential role for the tran ...... ment of natural killer T cells
@ast
An essential role for the tran ...... ment of natural killer T cells
@en
An essential role for the tran ...... ment of natural killer T cells
@nl
type
label
An essential role for the tran ...... ment of natural killer T cells
@ast
An essential role for the tran ...... ment of natural killer T cells
@en
An essential role for the tran ...... ment of natural killer T cells
@nl
prefLabel
An essential role for the tran ...... ment of natural killer T cells
@ast
An essential role for the tran ...... ment of natural killer T cells
@en
An essential role for the tran ...... ment of natural killer T cells
@nl
P2093
P2860
P356
P1433
P1476
An essential role for the tran ...... ment of natural killer T cells
@en
P2093
Ananda W Goldrath
Jamie Knell
Jessica K Fujimoto
Louise M D'Cruz
P2860
P304
P356
10.1038/NI.1845
P407
P577
2010-02-14T00:00:00Z