Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity
about
Clinical potential of vorapaxar in cardiovascular risk reduction in patients with atherosclerosisG-protein-coupled receptors signaling pathways in new antiplatelet drug developmentThrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADPBivalirudin in percutaneous coronary interventionRole of protease-activated and ADP receptor subtypes in thrombin generation on human plateletsPreparation of anhydrothrombin and characterization of its interaction with natural thrombin substratesPharmacokinetic drug evaluation of vorapaxar for secondary prevention after acute coronary syndrome.Purification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus.Differential signaling by protease-activated receptors: implications for therapeutic targeting.Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.Aprotinin: is it prothrombotic?An immunohistochemical analysis of tissue thrombin expression in the human atriaBivalirudin is a dual inhibitor of thrombin and collagen-dependent platelet activation in patients undergoing percutaneous coronary intervention.Involvement of the Na+/H+ exchanger in membrane phosphatidylserine exposure during human platelet activation.Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets.A serine protease zymogen functions as a pattern-recognition receptor for lipopolysaccharides.Protease-activated receptors in cancer: A systematic review.The Yin-Yang of thrombin and activated protein C.Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cellsPlatelet thrombin receptor antagonism and atherothrombosisProtease activated receptor-1 (PAR-1) mediated platelet aggregation is dependent on clopidogrel response.Thrombin receptor antagonism -the potential of antiplatelet medication SCH 530348.Platelet biology and implications for antiplatelet therapy in atherothrombotic disease.Antiplatelet therapy: thrombin receptor antagonists.PAR-1 antagonists: current state of evidence.Atopaxar: a review of its mechanism of action and role in patients with coronary artery disease.New horizons in platelet research: understanding and harnessing platelet functional diversity.Platelet thrombin receptor antagonism with vorapaxar: pharmacology and clinical trial development.Protease-activated receptors and their biological role - focused on skin inflammation.Thrombin receptor antagonism in antiplatelet therapy.A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.Antiplatelet and antithrombotic effect of F 16618, a new thrombin proteinase-activated receptor-1 (PAR1) antagonist.Pharmacokinetics and pharmacodynamics of the novel PAR-1 antagonist vorapaxar in patients with end-stage renal disease.Identification of signal transduction pathways involved in the formation of platelet subpopulations upon activation.PGE2 and PAR-1 in pulmonary fibrosis: a case of biting the hand that feeds you?PAR-1 genotype influences platelet aggregation and procoagulant responses in patients with coronary artery disease prior to and during clopidogrel therapy.A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1.The Plasma Membrane as a Reservoir, Protective Shield, and Light-Triggered Launch Pad for Peptide Therapeutics.Flavonoid-mediated inhibition of actin polymerization in cold-activated platelets.
P2860
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P2860
Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Protease-activated receptor 1 ...... platelet procoagulant activity
@ast
Protease-activated receptor 1 ...... platelet procoagulant activity
@en
Protease-activated receptor 1 ...... platelet procoagulant activity
@nl
type
label
Protease-activated receptor 1 ...... platelet procoagulant activity
@ast
Protease-activated receptor 1 ...... platelet procoagulant activity
@en
Protease-activated receptor 1 ...... platelet procoagulant activity
@nl
prefLabel
Protease-activated receptor 1 ...... platelet procoagulant activity
@ast
Protease-activated receptor 1 ...... platelet procoagulant activity
@en
Protease-activated receptor 1 ...... platelet procoagulant activity
@nl
P2093
P2860
P356
P1476
Protease-activated receptor 1 ...... platelet procoagulant activity
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.20.11189
P407
P577
1999-09-28T00:00:00Z