Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1
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Is urotensin-II the new endothelin?The role of urotensin II in cardiovascular and renal physiology and diseasesElevated plasma levels of human urotensin-II immunoreactivity in congestive heart failureThe expression of urotensin II receptor (U2R) is up-regulated by interferon-gammaUrotensin II: ancient hormone with new functions in vertebrate body fluid regulationBiochemical and functional characterization of high-affinity urotensin II receptors in rat cortical astrocytes[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in manThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features.Protein expression of urotensin II, urotensin-related peptide and their receptor in the lungs of patients with lymphangioleiomyomatosisInotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptorEndogenous urotensin II selectively modulates erectile function through eNOSDiscovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system.Cardiostimulant effects of urotensin-II in human heart in vitro.Identification and pharmacological characterization of native, functional human urotensin-II receptors in rhabdomyosarcoma cell lines.In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5,DTrp7,Dab8]urotensin II(4-11) (UFP-803)Potential Clinical Implications of the Urotensin II Receptor Antagonists.Vasoconstrictive effects of endothelin-1, endothelin-3, and urotensin II in isolated perfused human lungs and isolated human pulmonary arteries.Urotensin-II and the cardiovascular system--the importance of developing modulators.Urotensin-II induces ear flushing in ratsA closer look at the role of urotensin II in the metabolic syndrome.Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma.Plasma urotensin-2 level and Thr21Met but not Ser89Asn polymorphisms of the urotensin-2 gene are associated with migraines.Therapeutic targets in hypertension: is there a place for antagonists of the most potent vasoconstrictors?Urotensin II in cardiovascular regulation.Effect of the urotensin-II receptor antagonist palosuran on secretion of and sensitivity to insulin in patients with Type 2 diabetes mellitus.Acute Effect of Central Administration of Urotensin II on Baroreflex and Blood Pressure in Conscious Normotensive Rabbits.Role of urotensin II in health and disease.Urotensin-II Ligands: An Overview from Peptide to Nonpeptide StructuresPalosuran treatment effective as bosentan in the treatment model of pulmonary arterial hypertension.Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues.Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease.Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.A new ligand for the urotensin II receptor.Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.Update on the urotensinergic system: new trends in receptor localization, activation, and drug designUrantide: an ultrapotent urotensin II antagonist peptide in the rat aorta.Urotensin II evokes potent vasoconstriction in humans in vivo.A new therapeutic approach to erectile dysfunction: urotensin-II receptor high affinity agonist ligands.Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice.
P2860
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P2860
Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Orphan-receptor ligand human u ...... or responses with endothelin-1
@ast
Orphan-receptor ligand human u ...... or responses with endothelin-1
@en
Orphan-receptor ligand human u ...... or responses with endothelin-1
@nl
type
label
Orphan-receptor ligand human u ...... or responses with endothelin-1
@ast
Orphan-receptor ligand human u ...... or responses with endothelin-1
@en
Orphan-receptor ligand human u ...... or responses with endothelin-1
@nl
prefLabel
Orphan-receptor ligand human u ...... or responses with endothelin-1
@ast
Orphan-receptor ligand human u ...... or responses with endothelin-1
@en
Orphan-receptor ligand human u ...... or responses with endothelin-1
@nl
P2860
P3181
P356
P1476
Orphan-receptor ligand human u ...... or responses with endothelin-1
@en
P2093
A P Davenport
P2860
P3181
P356
10.1038/SJ.BJP.0703601
P407
P577
2000-10-01T00:00:00Z