Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.
about
The expression of urotensin II receptor (U2R) is up-regulated by interferon-gammaUrotensin II: ancient hormone with new functions in vertebrate body fluid regulationBiochemical and functional characterization of high-affinity urotensin II receptors in rat cortical astrocytesThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features.Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticityUrotensin II inhibits skeletal muscle glucose transport signaling pathways via the NADPH oxidase pathway.Renal impairment, hypertension and plasma urotensin II.Identification and pharmacological characterization of native, functional human urotensin-II receptors in rhabdomyosarcoma cell lines.The urotensin system is up-regulated in the pre-hypertensive spontaneously hypertensive ratThe peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systemsPotential Clinical Implications of the Urotensin II Receptor Antagonists.Urotensin-II and the cardiovascular system--the importance of developing modulators.Urotensin-II induces ear flushing in ratsUrotensin II in invertebrates: from structure to function in Aplysia californica.Urotensin II contributes to the formation of lung adenocarcinoma inflammatory microenvironment through the NF-κB pathway in tumor-bearing nude mice.Comparative understanding of UTS2 and UTS2R genes for their involvement in type 2 diabetes mellitus.Discovery of new antagonists aimed at discriminating UII and URP-mediated biological activities: insight into UII and URP receptor activation.The Urotensin II System and Carotid Atherosclerosis: A Role in Vascular CalcificationUrotensin-II Ligands: An Overview from Peptide to Nonpeptide StructuresUrotensin-II receptor is over-expressed in colon cancer cell lines and in colon carcinoma in humans.RGS2 regulates urotensin II-induced intracellular Ca2+ elevation and contraction in glomerular mesangial cells.Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375.Update on the urotensinergic system: new trends in receptor localization, activation, and drug designDeletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice.Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart.The effects of urotensin II and urantide on forearm blood flow and systemic haemodynamics in humans.Urotensin-II: More Than a Mediator for Kidney.The vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation.New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide.An investigation into the origin of the biased agonism associated with the urotensin II receptor activation.Urantide conformation and interaction with the urotensin-II receptor.
P2860
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P2860
Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Molecular and pharmacological ...... ors from the mouse and monkey.
@en
type
label
Molecular and pharmacological ...... ors from the mouse and monkey.
@en
prefLabel
Molecular and pharmacological ...... ors from the mouse and monkey.
@en
P2093
P2860
P356
P1476
Molecular and pharmacological ...... ors from the mouse and monkey.
@en
P2093
Beverly E Maleeff
Diane Naselsky
Graham Duddy
Jan L Sechler
Jyoti Disa
Nabil A Elshourbagy
Nambi V Aiyar
Stephen A Douglas
Stephen Harrison
Usman Shabon
P2860
P356
10.1038/SJ.BJP.0704671
P407
P577
2002-05-01T00:00:00Z