Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor
about
Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductaseDap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiaeSpectroscopic and biochemical characterization of heme binding to yeast Dap1p and mouse PGRMC1pMeasurement of the heme affinity for yeast dap1p, and its importance in cellular functionRegulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of FerrochelataseChemogenomic profiling on a genome-wide scale using reverse-engineered gene networksCYB5D2 requires heme-binding to regulate HeLa cell growth and confer survival from chemotherapeutic agentsNovel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae.The neuroprotective steroid progesterone promotes mitochondrial uncoupling, reduces cytosolic calcium and augments stress resistance in yeast cellsPgrmc1 (progesterone receptor membrane component 1) associates with epidermal growth factor receptor and regulates erlotinib sensitivity.Functional annotation of hierarchical modularityS2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling.Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors.Progesterone receptor membrane component 1 deficiency attenuates growth while promoting chemosensitivity of human endometrial xenograft tumorsAnalyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation.Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1.The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility.Progesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors.Influence of protein-protein interactions on the cellular localization of cytochrome P450.PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding.Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics.Role of ferroxidases in iron uptake and virulence of Cryptococcus neoformans.Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450.Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy.PGRMC1: a new biomarker for the estrogen receptor in breast cancer.PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.Insulin receptor plasma membrane levels increased by the progesterone receptor membrane component 1.
P2860
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P2860
Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@ast
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@en
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@nl
type
label
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@ast
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@en
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@nl
prefLabel
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@ast
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@en
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@nl
P2093
P2860
P1433
P1476
Saccharomyces cerevisiae Dap1p ...... sociated progesterone receptor
@en
P2093
Martin Bard
Randal A Hand
Rolf J Craven
P2860
P304
P356
10.1128/EC.2.2.306-317.2003
P407
P577
2003-04-01T00:00:00Z