Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain - Wikidata - awgldk - TriplyDB

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

http://www.wikidata.org/entity/Q24676619

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Structure--function relationships in HIV-1 Nef.Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation HIV: master of the host cell.The enduring tale of T cells in HIV immunopathogenesis Apoptosis in animal models of virus-induced disease Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRζ fragments The HIV-1 Nef protein as a target for antiretroviral therapy.Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques.Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.Molecular interactions of human immunodeficiency virus type 1 with primary human oral keratinocytes.A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef Expression of CD154 by a simian immunodeficiency virus vector induces only transitory changes in rhesus macaques.Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleuk Human immunodeficiency virus type 1 induces apoptosis in CD4(+) but not in CD8(+) T cells in ex vivo-infected human lymphoid tissue In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivity Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter.Using death to one's advantage: HIV modulation of apoptosis.Cellular immune responses to HIV.Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.Cytopathic killing of peripheral blood CD4(+) T lymphocytes by human immunodeficiency virus type 1 appears necrotic rather than apoptotic and does not require env.Different effects of Nef-mediated HLA class I down-regulation on human immunodeficiency virus type 1-specific CD8(+) T-cell cytolytic activity and cytokine production.The SCHOOL of nature: III. From mechanistic understanding to novel therapies CD4+ T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis.Human immunodeficiency virus-1 (HIV-1)-mediated apoptosis: new therapeutic targets.Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.Human retroviruses after 20 years: a perspective from the past and prospects for their future control.Early changes in T-cell activation predict antiretroviral success in salvage therapy of HIV infection Inhibition of T-cell receptor signal transduction and viral expression by the linker for activation of T cells-interacting p12(I) protein of human T-cell leukemia/lymphoma virus type 1.Apoptosis of HIV-specific CD8+ T cells: an HIV evasion strategy.Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef Herpes simplex virus type 1 infection of activated cytotoxic T cells: Induction of fratricide as a mechanism of viral immune evasion Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways.

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Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

http://www.wikidata.org/entity/Q24676619

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1999 nî lūn-bûn

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1999 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1999 թվականի մայիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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Journal of Experimental Medicine

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Induction of Fas ligand expres ...... the T cell receptor zeta chain

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A J McMichael

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A S Baur

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B Laffert

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D Wolf

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G R Screaton

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J Mongkolsapay

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M Kraft

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W Kolanus

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X N Xu

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P2860

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

The Fas death factor

Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes.

Programmed cell death and AIDS: from hypothesis to experiment.

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1489-96

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10.1084/JEM.189.9.1489

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9

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189

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13074749

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10224289

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2193060

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