Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.
about
P1343
Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I traffickingSmall molecule inhibitors of the HIV-1 virulence factor, NefRegulation of focal adhesion targeting and inhibitory functions of the FAK related protein FRNK using a novel estrogen receptor "switch".Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytesLatent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1.Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation.Mechanisms of HIV-1 Nef function and intracellular signaling.M-CSF-mediated macrophage differentiation but not proliferation is correlated with increased and prolonged ERK activation.HIV-1 Nef promotes survival of TF-1 macrophages by inducing Bcl-XL expression in an extracellular signal-regulated kinase-dependent manner.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid raftsNef interference with HIV-1-specific CTL antiviral activity is epitope specific.HIV-1 Nef regulates the release of superoxide anions from human macrophages.
P2860
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P2860
Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.
description
2001 nî lūn-bûn
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2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2001 թվականի հունվարին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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name
Design and use of an inducibly ...... ef to study immune modulation.
@ast
Design and use of an inducibly ...... ef to study immune modulation.
@en
type
label
Design and use of an inducibly ...... ef to study immune modulation.
@ast
Design and use of an inducibly ...... ef to study immune modulation.
@en
prefLabel
Design and use of an inducibly ...... ef to study immune modulation.
@ast
Design and use of an inducibly ...... ef to study immune modulation.
@en
P2093
P2860
P1433
P1476
Design and use of an inducibly ...... ef to study immune modulation.
@en
P2093
D M Rekosh
K S Ravichandran
M Alexander
M L Hammarskjold
P2860
P304
P356
10.1128/JVI.75.2.834-843.2001
P4510
P577
2001-01-01T00:00:00Z