The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease - Wikidata - awgldk - TriplyDB

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

http://www.wikidata.org/entity/Q24678328

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The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure Ironing out Ferroportin Distribution of manganese and other biometals in flatiron mice Atherogenesis and iron: from epidemiology to cellular level.Is low iron status a risk factor for neural tube defects?Human macrophage ferroportin biology and the basis for the ferroportin disease.The core control system of intracellular iron homeostasis: a mathematical model.Host iron withholding demands siderophore utilization for Candida glabrata to survive macrophage killing.Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice Hereditary hemochromatosis and transferrin receptor 2 Ferroportin deficiency impairs manganese metabolism in flatiron mice.The molecular mechanism of hepcidin-mediated ferroportin down-regulation.Nramp1 and Other Transporters Involved in Metal Withholding during Infection.Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations.The genetics of essential metal homeostasis during development Forging a field: the golden age of iron biology.Iron depletion limits intracellular bacterial growth in macrophages Flatiron mice and ferroportin disease.Ferroportin-mediated iron transport: expression and regulation.Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.Hepcidin regulation of iron transport Testing the iron hypothesis in a mouse model of atherosclerosis.Leishmania-mediated inhibition of iron export promotes parasite replication in macrophages.Zebrafish in the sea of mineral (iron, zinc, and copper) metabolism."Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels Ironing out the wrinkles in host defense: interactions between iron homeostasis and innate immunity.The molecular basis of iron overload disorders and iron-linked anemias.Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice.Hepcidin and ferroportin: the new players in iron metabolism Role of ferroportin in macrophage-mediated immunity Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype.Ironing Out the Unconventional Mechanisms of Iron Acquisition and Gene Regulation in Chlamydia.Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion.Multiple regulatory mechanisms act in concert to control ferroportin expression and heme iron recycling by macrophages Crosstalk between Iron Metabolism and Erythropoiesis.Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice.Ferroportin disease: pathogenesis, diagnosis and treatment.High levels of iron supplementation prevents neural tube defects in the Fpn1ffe mouse model.

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The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease

http://www.wikidata.org/entity/Q24678328

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2007 nî lūn-bûn

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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The flatiron mutation in mouse ...... e to cause ferroportin disease

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The flatiron mutation in mouse ...... e to cause ferroportin disease

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The flatiron mutation in mouse ...... e to cause ferroportin disease

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The flatiron mutation in mouse ...... e to cause ferroportin disease

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Amaru J Sanchez

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Diane McVey Ward

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Irene E Zohn

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Ivana De Domenico

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Jerry Kaplan

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Jessica F Goodman

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Xiayun Liang

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P2860

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells

A phenotype-based screen for embryonic lethal mutations in the mouse.

Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

The ferroportin disease

Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

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4174-4180

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