Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.
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Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitinationIneffective erythropoiesis and thalassemiasHepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in miceThe role of ferric carboxymaltose in the treatment of iron deficiency anemia in patients with gastrointestinal diseaseIron deficiency anemia in inflammatory bowel diseaseBody iron delocalization: the serious drawback in iron disorders in both developing and developed countriesIroning out FerroportinAge-dependent expression of duodenal cytochrome b, divalent metal transporter 1, ferroportin 1, and hephaestin in the duodenum of ratsMomelotinib in myelofibrosis: JAK1/2 inhibitor with a role in treating and understanding the anemia.Protein degradation and iron homeostasisFuture alternative therapies for β-thalassemia.Targeting Iron Homeostasis in Acute Kidney Injury.Ceruloplasmin-ferroportin system of iron traffic in vertebrates.Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation.Iron Loading and Overloading due to Ineffective Erythropoiesis.Growth differentiation factor 15 in erythroid health and disease.Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages.Hepcidin is involved in iron regulation in the ischemic brain.Prolactin (PRL)-stimulated ubiquitination of ZnT2 mediates a transient increase in zinc secretion followed by ZnT2 degradation in mammary epithelial cells.Diagnosis and management of iron deficiency anemia in patients with IBD.The role of iron in the immune response to bacterial infectionInduction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux.Iron metabolism in thalassemia and sickle cell diseaseCross-talk between iron homeostasis and intestinal inflammation.Diagnosis and management of iron deficiency anemia in the 21st century.Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in miceIron and immunity: immunological consequences of iron deficiency and overload.A systems biology approach to iron metabolism.Reducing iron accumulation: A potential approach for the prevention and treatment of postmenopausal osteoporosisEffects of developmental iron deficiency and post-weaning iron repletion on the levels of iron transporter proteins in rats.Molecular insights into the regulation of iron metabolism during the prenatal and early postnatal periods.Ferroportin-mediated iron transport: expression and regulation.Expression and function of iron-regulatory proteins in retina.Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.Iron transport machinery of human cells: players and their interactions.Iron homeostasis in the liver.Molecular mechanisms of normal iron homeostasis.The molecular basis of iron overload disorders and iron-linked anemias.Hepcidin and ferroportin: the new players in iron metabolismControl of systemic iron homeostasis by the hemojuvelin-hepcidin axis.
P2860
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P2860
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@en
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@nl
type
label
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@en
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@nl
prefLabel
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@en
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@nl
P2093
P2860
P356
P1476
Hepcidin-induced internalizati ...... erative interaction with Jak2.
@en
P2093
Diane M Ward
Ivana De Domenico
Jerry Kaplan
P2860
P304
P356
10.1073/PNAS.0900453106
P407
P577
2009-02-20T00:00:00Z