Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis - Wikidata - awgldk - TriplyDB

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

http://www.wikidata.org/entity/Q24679619

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Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß NEDD9 is a positive regulator of epithelial-mesenchymal transition and promotes invasion in aggressive breast cancer Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway Autocrine PDGFR signaling promotes mammary cancer metastasis Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition Identifying and targeting tumor-initiating cells in the treatment of breast cancer Rebuilding cancer metastasis in the mouse Targeting TGF-β signaling in cancer MicroRNA expression characterizes oligometastasis(es)Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis TGFbeta in Cancer Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis Altered gene expression profile in mouse bladder cancers induced by hydroxybutyl(butyl)nitrosamine.Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells.BMP7: a new bone metastases prevention?The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.Smad4-expression is decreased in breast cancer tissues: a retrospective study.Expression profiling of genes regulated by TGF-beta: differential regulation in normal and tumour cells.EMT tumorigenesis in the mouse mammary gland.Convergence of p53 and transforming growth factor beta (TGFbeta) signaling on activating expression of the tumor suppressor gene maspin in mammary epithelial cells.The type III TGF-beta receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-beta signaling.TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism.TGF-beta biology in mammary development and breast cancer.Transforming growth factor beta (TGF-beta) and inflammation in cancer.Mammary development and breast cancer: the role of stem cells HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.SFRP1 reduction results in an increased sensitivity to TGF-β signaling.A context-specific role for retinoblastoma protein-dependent negative growth control in suppressing mammary tumorigenesis.Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer TGFBR1 and cancer susceptibility.

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Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

http://www.wikidata.org/entity/Q24679619

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Transforming growth factor bet ...... promoting pulmonary metastasis

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Peter M Siegel

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Robert D Cardiff

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Weiping Shu

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William J Muller

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P2860

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models

TGFbeta signaling in growth control, cancer, and heritable disorders

Regulation of immune responses by TGF-beta

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation

Dissemination and growth of cancer cells in metastatic sites

TGF-beta signaling in tumor suppression and cancer progression

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

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Joan Massagué Solé

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