Human premature aging, DNA repair and RecQ helicases - Wikidata - awgldk - TriplyDB

Human premature aging, DNA repair and RecQ helicases

Human premature aging, DNA repair and RecQ helicases

http://www.wikidata.org/entity/Q24680996

about

Unwinding and rewinding: double faces of helicase?Human RECQL5 participates in the removal of endogenous DNA damage Roles of Werner syndrome protein in protection of genome integrity Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging DNA mismatch repair: molecular mechanism, cancer, and ageing DNA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of Radioresistance G-quadruplexes and helicases Photosensitive human syndromes Disease-causing missense mutations in human DNA helicase disorders Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.c-Myc accelerates S-phase and requires WRN to avoid replication stress The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.MitoInteractome: mitochondrial protein interactome database, and its application in 'aging network' analysis Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase Meiosis genes in Daphnia pulex and the role of parthenogenesis in genome evolution.dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila.Replication protein A stimulates the Werner syndrome protein branch migration activity.Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity The involvement of human RECQL4 in DNA double-strand break repair.WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3 Mechanistic and biological aspects of helicase action on damaged DNA.Distinct roles of RECQ1 in the maintenance of genomic stability.Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.The UvrD303 hyper-helicase exhibits increased processivity.Rapid purification of helicase proteins and in vitro analysis of helicase activity.Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding.Delineation of WRN helicase function with EXO1 in the replicational stress response Molecular analyses of DNA helicases involved in the replicational stress response.Premature aging and cancer in nucleotide excision repair-disorders.G-quadruplex nucleic acids and human disease DNA repair deficiency in neurodegeneration.Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4.The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.Characterization of biochemical properties of Bacillus subtilis RecQ helicase The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair.Accelerated in vivo epidermal telomere loss in Werner syndrome.The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation.

P2860

Q21296726-A1693162-3E97-4472-8695-0EB13E092359 Q24298591-B9D2D718-1045-4EE4-ACD8-3577CB1BE1C0 Q24643050-7FC546F6-548C-4C74-9410-EDB5D4D4554A Q24646853-D7C13E2E-EE8A-419A-B178-37D5B75D5A53 Q24647002-88675038-2AE9-4B0C-A9AD-E5BAF9B47804 Q26738556-7228F422-3C7A-4952-AF1C-9C1865E93A25 Q26765428-0BFBFC7A-ADF0-4154-BA0A-4AD7D86508EC Q26800642-BC58BCF9-139F-4BF0-B6AA-03675527FD52 Q26828898-0F14616B-AA0B-4172-91BF-DC487AAC6677 Q27318290-BF012D0C-A5B3-48C4-B23B-E6A33F70A158 Q27347951-EAB56D44-FC1C-4FC9-B1C2-28B93D4535BD Q28475013-B2B31D35-562E-41E3-87E0-649FD1633771 Q30687417-68B33E8B-D15E-4B3F-B301-B3E435E5408A Q30950507-0C3361F3-18C4-4714-B263-0C962A8512B3 Q33347075-0DA014C5-67B5-4BA5-BC90-4CFB52749942 Q33433256-F33D2E81-655A-46E5-8D7A-7933267F93CC Q33477414-DD88BB82-616E-4ADD-BD12-060ADC6F2C7C Q33509276-188E9DEB-8854-4290-BCE7-4CD78D55D767 Q33531417-E00FC69D-C3B0-415E-94D5-20AFE03E9D84 Q33539979-84B71001-D4DC-427F-922F-12EC9B41D10F Q33588653-60AFA67B-C233-40E8-B7F8-4CD55D9A1BC7 Q33614603-18CBFD25-6461-430C-9445-BC6AD96140D0 Q33684409-5FDF33DF-C18A-4D30-8A73-78B53F27C01C Q33700136-D85CC5E4-81E5-417B-B2DF-69B7AF1F4AB4 Q33761309-4021F8A4-4B5E-4759-8F35-5D391E16D2A9 Q33943342-2FAD0F0F-AA35-428C-8A95-A4DB341CD864 Q33945585-124DE65E-5A25-4462-91B9-6D2D2A1DED49 Q33945750-E48D98C6-9BEC-4898-A871-48FCD1DF6FCF Q33976698-F6F90C1B-8871-4429-B7C1-1092189B92F3 Q34025252-CDED1B6C-D212-4E2F-B4F1-F0374E86CF9A Q34073316-2BF89F50-B52F-4540-9AE9-ABDEB18248AE Q34183328-07DF4043-76C7-42C6-9B60-5832FFD2FD64 Q34313069-6F73D79D-376C-4E50-9EA9-CF3AC157FD65 Q34324403-C01BB2AE-3A6B-4320-9452-FE43D3A249D4 Q34511859-FB9EA34D-9484-4944-B090-08D66D7CF881 Q34534194-BBB3B9C3-C2AF-4081-A1D1-F78C84764CA5 Q34593441-C734C6D3-BDB6-4DC6-8DBA-567D32A869AA Q34743439-B79A3C8E-E429-49A4-ADDF-19906C88F5BB Q35052092-9AF76AA8-728D-414B-8323-9B475CC58B73 Q35142283-6200FFA7-F0AC-41DA-BEA8-5AF38EDBA781

P2860

Human premature aging, DNA repair and RecQ helicases

http://www.wikidata.org/entity/Q24680996

description

2007 nî lūn-bûn

@nan

2007 թուականին հրատարակուած գիտական յօդուած

@hyw

2007 թվականին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Human premature aging, DNA repair and RecQ helicases

@ast

Human premature aging, DNA repair and RecQ helicases

@en

Human premature aging, DNA repair and RecQ helicases

@nl

type

label

Human premature aging, DNA repair and RecQ helicases

@ast

Human premature aging, DNA repair and RecQ helicases

@en

Human premature aging, DNA repair and RecQ helicases

@nl

prefLabel

Human premature aging, DNA repair and RecQ helicases

@ast

Human premature aging, DNA repair and RecQ helicases

@en

Human premature aging, DNA repair and RecQ helicases

@nl

P1433

Q24680996-4C199397-80BB-405D-B6C4-581082B2B2F4

P1476

Q24680996-9359C80E-D31C-4EDA-8B95-BCECFA4DBD00

P2093

Q24680996-A73BB9F9-CA86-44D5-ADBC-0FA86BFCF430

Q24680996-D6254E5C-A722-4B1E-8C48-C8C5DADFA011

P275

Q24680996-2D5E2A54-B410-44E1-BA2B-1798AF209D98

P2860

Q24680996-0030D00E-F6B7-4244-8A13-D9F0C2C18CBA

Q24680996-04949506-D8CB-40E5-84F4-27B58C58CD11

Q24680996-0517B590-63CC-41FF-9DFF-155F78448309

Q24680996-060E966D-E910-48A7-9700-3411D5112523

Q24680996-09DC885D-B233-4CD3-A9F4-48E61AD4B69C

Q24680996-0E1C2E70-FE9C-4629-9AFF-A6D3EB824ECD

Q24680996-1377BFF6-A51B-4370-8C9E-03E2E25E62D0

Q24680996-140BE9AA-2279-43B0-B795-D4C57D76DDDD

Q24680996-15084C12-20CB-4ADF-BD96-60B8529E9618

Q24680996-1709333A-E5DE-44EE-A524-37F7EB05764F

P304

Q24680996-A52FA257-4577-42EE-976F-E3C8A8A53228

P31

Q24680996-BB1311B1-3180-4CDA-950C-52C11557C06D

Q24680996-CBDB7FF8-DA56-44A7-9FD0-155D25FEFDA8

P3181

Q24680996-60D3EF07-76A0-4436-8F2A-4383110336F6

P356

Q24680996-791841A6-191F-4195-AD14-15988ED44A00

P407

Q24680996-B39FB9D3-DDF0-4CE2-AE94-5A0E5047CEC6

P433

Q24680996-FE8B18E0-E688-48BD-BC6F-B9AFD2FD26EA

P478

Q24680996-A676B4CD-1B0D-4DAC-BAC7-D510D2BEAC91

P577

Q24680996-2437A360-EFA1-4865-B320-44B7E601C66B

Q24680996-9BBCB786-808F-450A-B2AF-317759376520

P5875

Q24680996-369481BD-A356-4145-BBC3-9276F11045A6

P698

Q24680996-4AD71BCD-2E25-45B7-A5C4-EF8FCE86B04F

P921

Q24680996-75BB1E8C-CE9E-4ECE-A462-80611A272D9C

Q24680996-9BA8CE1A-5254-44B8-87BC-502451996634

P932

Q24680996-89226201-EDC4-47EC-B965-2CCF8739131F

P3181

P356

P1433

Nucleic Acids Research

P1476

Human premature aging, DNA repair and RecQ helicases

@en

P2093

Robert M Brosh

http://www.w3.org/2001/XMLSchema#string

Vilhelm A Bohr

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution-NonCommercial

P2860

Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Functional and physical interaction between WRN helicase and human replication protein A

Normal human chromosomes have long G-rich telomeric overhangs at one end

Crystal structure of parallel quadruplexes from human telomeric DNA

Instability and decay of the primary structure of DNA

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

Ku complex interacts with and stimulates the Werner protein

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

p53 Modulates the exonuclease activity of Werner syndrome protein

P304

7527-44

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4436108

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/NAR/GKM1008

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

35

http://www.w3.org/2001/XMLSchema#string

P577

2007-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

2007-11-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5839646

http://www.w3.org/2001/XMLSchema#string

P698

18006573

http://www.w3.org/2001/XMLSchema#string

P921

progeroid syndrome

P932

2190726

http://www.w3.org/2001/XMLSchema#string