The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation
about
The RecQ DNA helicases in DNA repairThe biology of DHX9 and its potential as a therapeutic targetPreventing replication fork collapse to maintain genome integrityWerner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsSingle-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicasesReplication protein A stimulates the Werner syndrome protein branch migration activity.Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN.Human RECQL1 participates in telomere maintenanceDNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding.Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase.Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loopsDNA end resection controls the balance between homologous and illegitimate recombination in Escherichia coli.Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteinsSMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication.Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation.DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonucleaseHuman RecQ helicases in DNA repair, recombination, and replication.Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16DTelomerase-independent paths to immortality in predictable cancer subtypes.An Overview of the Molecular Mechanisms of Recombinational DNA Repair.Prospects for the Use of ATR Inhibitors to Treat Cancer.Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences.Roles of DNA helicases in the mediation and regulation of homologous recombination.RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.
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P2860
The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The Werner syndrome helicase/e ...... anch migration and degradation
@ast
The Werner syndrome helicase/e ...... anch migration and degradation
@en
The Werner syndrome helicase/e ...... anch migration and degradation
@nl
type
label
The Werner syndrome helicase/e ...... anch migration and degradation
@ast
The Werner syndrome helicase/e ...... anch migration and degradation
@en
The Werner syndrome helicase/e ...... anch migration and degradation
@nl
prefLabel
The Werner syndrome helicase/e ...... anch migration and degradation
@ast
The Werner syndrome helicase/e ...... anch migration and degradation
@en
The Werner syndrome helicase/e ...... anch migration and degradation
@nl
P2860
P3181
P1433
P1476
The Werner syndrome helicase/e ...... anch migration and degradation
@en
P2093
Gregory Sowd
P2860
P3181
P356
10.1371/JOURNAL.PONE.0004825
P407
P577
2009-03-13T00:00:00Z