Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
about
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersNMNAT1 mutations cause Leber congenital amaurosisPleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammationUndercover: gene control by metabolites and metabolic enzymesAnalyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain lengthFunctional Aspects of PARP1 in DNA Repair and Transcription.Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferasesNew facets in the regulation of gene expression by ADP-ribosylation and poly(ADP-ribose) polymerases.High-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length.Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues.Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration.Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in DrosophilaTranscriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulationCrosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series.Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human DiseaseThe NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcriptionMolecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sitesSIRT1/PARP1 crosstalk: connecting DNA damage and metabolism.SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functionsPoly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.Reprogramming cellular events by poly(ADP-ribose)-binding proteinsDiversification of NAD biological role: the importance of location.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Mechanisms of distal axonal degeneration in peripheral neuropathies.Nicotinate/nicotinamide mononucleotide adenyltransferase-mediated regulation of NAD biosynthesis protects guard cells from reactive oxygen species in ABA-mediated stomatal movement in Arabidopsis.Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship.Nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi (TcNMNAT): a cytosol protein target for serine kinases.The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation.Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.Nicotinamide Mononucleotide Adenylyltransferase 1 Protects Neural Cells Against Ischemic Injury in Primary Cultured Neuronal Cells and Mouse Brain with Ischemic Stroke Through AMP-Activated Protein Kinase Activation.Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence.Localization and phosphorylation of Plasmodium falciparum nicotinamide/nicotinate mononucleotide adenylyltransferase (PfNMNAT) in intraerythrocytic stages
P2860
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P2860
Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@ast
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@en
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@nl
type
label
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@ast
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@en
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@nl
prefLabel
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@ast
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@en
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@nl
P2860
P3181
P356
P1476
Regulation of poly(ADP-ribose) ...... yme NMN adenylyl transferase 1
@en
P2093
Felicitas Berger
P2860
P304
P3181
P356
10.1073/PNAS.0609211104
P407
P577
2007-02-22T00:00:00Z