Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging. - Wikidata - awgldk - TriplyDB

Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.

Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.

http://www.wikidata.org/entity/Q37693027

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Functions of PARylation in DNA Damage Repair Pathways Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice.Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats Transition-state analysis of 2-O-acetyl-ADP-ribose hydrolysis by human macrodomain 1.Alteration of poly(ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation.Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1.PARP-1 deficiency blocks IL-5 expression through calpain-dependent degradation of STAT-6 in a murine asthma model.Poly(ADP-Ribosyl)ation Affects Histone Acetylation and Transcription.Pathophysiology of perinatal asphyxia: can we predict and improve individual outcomes?Cytotoxic and apoptotic effects of menadione on rat hepatocellular carcinoma cells Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4.Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation.Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.Natural inhibitors of poly(ADP-ribose) polymerase-1.Poly(ADP-ribose) polymerase 1 (PARP1) in atherosclerosis: from molecular mechanisms to therapeutic implications.Molecular evolutionary patterns of NAD+/Sirtuin aging signaling pathway across taxa.Flow signaling and atherosclerosis.New Quantitative Mass Spectrometry Approaches Reveal Different ADP-ribosylation Phases Dependent On the Levels of Oxidative Stress.MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction.PARP1 depletion induces RIG-I-dependent signaling in human cancer cells.

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Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging.

http://www.wikidata.org/entity/Q37693027

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scientific article published on 20 May 2009

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Poly(ADP-ribose) polymerase 1 ...... ess and inflammation in aging.

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Poly(ADP-ribose) polymerase 1 ...... ess and inflammation in aging.

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Matthias Altmeyer

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Michael O Hottiger

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P2860

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Superoxide dismutase 1 knock-down induces senescence in human fibroblasts

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

The power to reduce: pyridine nucleotides--small molecules with a multitude of functions

Motif module map reveals enforcement of aging by continual NF-kappaB activity

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

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458-469

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scholarly article

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10.18632/AGING.100052

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5

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1

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2009-05-20T00:00:00Z

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20157531

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2806023

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