A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells
about
TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks.Promising Gene Therapeutics for Salivary Gland RadiotoxicityTousled kinase TLK1B counteracts the effect of Asf1 in inhibition of histone H3-H4 tetramer formation.TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity.Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy.Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cellsTLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint.Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomiaThe multi-tasking P-TEFb complex.mars and tousled-like kinase act in parallel to ensure chromosome fidelity in Drosophila.Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2.Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.Adenoviral delivery of Tousled kinase for the protection of salivary glands against ionizing radiation damage.The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.The Tousled-Like Kinases as Guardians of Genome IntegrityTousled-like kinases modulate reactivation of gammaherpesviruses from latency.TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells.Preserving Salivary Gland Physiology against Genotoxic Damage - The Tousled Way.
P2860
Q21263009-6F80DB38-8942-404A-B07A-57821A76420EQ21263017-A8B2C75B-A7D0-416D-AD79-03CFFBD8BEB7Q30361268-819DF1BC-217C-438C-98CE-B109B4A30866Q33479765-6AA0C7B9-A441-4E19-8F86-E3B67B5DE329Q33519757-9C8FAEA6-B7B0-4C33-A1FB-336CA6F29584Q33540005-5DAC7BC3-EF64-4364-90F3-A197E395A325Q34942420-737E62BD-C4BB-410C-9EAA-2AB2112AA10FQ35917261-2C30ACEF-04D0-4F06-A123-09BB71E5CDABQ35918497-04D1538B-8834-474E-BF8A-B6EF9EA02A0EQ36945801-B2D6510B-9687-40AF-A0FD-5A3543331E99Q37177846-298F834F-4A36-405B-BC80-86ED4D170E30Q37249371-4275F6CA-B85F-428E-8E4C-AED435D2F763Q37621430-97FC48F7-D2DE-467E-B609-A54B9E555F18Q38679219-4D069BC5-0D3C-4CCB-A0A4-39C6AA46119BQ39277352-E264530E-FB45-41FB-8A07-806E07DC5DE0Q39529350-B1D5ED24-5CDD-489E-A546-AEAAEEB8A135Q41840260-F709EE32-C8F6-461A-AD5C-514EBAC43F46Q42274743-4C2AB836-17AD-4737-91C5-F5E006E949FEQ47869993-2379F0A1-AB4E-41C6-80BF-97F3F2CE3635Q48253483-56AFB4B6-1938-43DB-A916-E68BC0DC3270Q48267593-294ACE72-2CAE-4332-9D2B-F9EED4DB4631Q49565489-447DAE38-E7CE-4D7F-A184-7B8D2D0716E2
P2860
A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A dominant negative mutant of ...... normal breast epithelial cells
@ast
A dominant negative mutant of ...... normal breast epithelial cells
@en
A dominant negative mutant of ...... normal breast epithelial cells
@nl
type
label
A dominant negative mutant of ...... normal breast epithelial cells
@ast
A dominant negative mutant of ...... normal breast epithelial cells
@en
A dominant negative mutant of ...... normal breast epithelial cells
@nl
prefLabel
A dominant negative mutant of ...... normal breast epithelial cells
@ast
A dominant negative mutant of ...... normal breast epithelial cells
@en
A dominant negative mutant of ...... normal breast epithelial cells
@nl
P2093
P2860
P356
P1433
P1476
A dominant negative mutant of ...... normal breast epithelial cells
@en
P2093
Arrigo De Benedetti
Briana Williams
Gulshan Sunavala-Dossabhoy
P2860
P2888
P356
10.1186/1471-2121-4-16
P407
P577
2003-10-28T00:00:00Z
P5875
P6179
1053117720