Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens
about
Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataractInteractions between small heat shock protein alpha-crystallin and galectin-related interfiber protein (GRIFIN) in the ocular lensThe role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration.The common modification in alphaA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model.Degradation of C-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway.A conserved role of αA-crystallin in the development of the zebrafish embryonic lens.Novel roles for α-crystallins in retinal function and disease.Alpha-crystallin-derived peptides as therapeutic chaperones.Changes in zebrafish (Danio rerio) lens crystallin content during developmentImportance of eye lens α-crystallin heteropolymer with 3:1 αA to αB ratio: stability, aggregation, and modifications.Comparative proteomic analysis identifies age-dependent increases in the abundance of specific proteins after deletion of the small heat shock proteins αA- and αB-crystallin.Differential role of arginine mutations on the structure and functions of α-crystallin.Protein-protein interactions and lens transparency.Molecular chaperones as regulators of cell death.Loss of the small heat shock protein αA-crystallin does not lead to detectable defects in early zebrafish lens development.Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent αA(ins)-Crystallin Encode Activated ChaperonesDifferential binding of mutant (R116C) and wildtype alphaA crystallin to actin.Synergistic transcription activation by Maf and Sox and their subnuclear localization are disrupted by a mutation in Maf that causes cataract.Acetylation of lysine 92 improves the chaperone and anti-apoptotic activities of human αB-crystallin.Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability.Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells.Role of cysteine residues in the enhancement of chaperone function in methylglyoxal-modified human alpha A-crystallin.
P2860
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P2860
Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Morphological characterization ...... lin double knockout mouse lens
@ast
Morphological characterization ...... lin double knockout mouse lens
@en
Morphological characterization ...... lin double knockout mouse lens
@nl
type
label
Morphological characterization ...... lin double knockout mouse lens
@ast
Morphological characterization ...... lin double knockout mouse lens
@en
Morphological characterization ...... lin double knockout mouse lens
@nl
prefLabel
Morphological characterization ...... lin double knockout mouse lens
@ast
Morphological characterization ...... lin double knockout mouse lens
@en
Morphological characterization ...... lin double knockout mouse lens
@nl
P2093
P2860
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P356
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Morphological characterization ...... lin double knockout mouse lens
@en
P2093
Daniel L Boyle
Eric F Wawrousek
James P Brady
Larry Takemoto
P2860
P2888
P356
10.1186/1471-2415-3-3
P407
P577
2003-01-24T00:00:00Z
P5875
P6179
1009223272