Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells - Wikidata - awgldk - TriplyDB

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

http://www.wikidata.org/entity/Q24798304

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SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer Association analyses identify six new psoriasis susceptibility loci in the Chinese population Global gene expression profiling of cells overexpressing SMC3.Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade.Critical differences between isoforms of securin reveal mechanisms of separase regulation Effect of PTTG on endogenous gene expression in HEK 293 cells.Meta-analysis of several gene lists for distinct types of cancer: a simple way to reveal common prognostic markers.Immortalized cells and one oncogene in malignant transformation: old insights on new explanation.Transfer of malignant trait to immortalized human cells following exposure to human cancer serum.Withaferin A synergizes the therapeutic effect of doxorubicin through ROS-mediated autophagy in ovarian cancer Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation.Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target High expression of pituitary tumor-transforming gene-1 predicts poor prognosis in clear cell renal cell carcinoma.Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin.MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines.Alteration of Pituitary Tumor Transforming Gene-1 Regulates Trophoblast Invasion via the Integrin/Rho-Family Signaling Pathway Synergistic cytotoxic action of cisplatin and withaferin A on ovarian cancer cell lines.PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.Identification of potential therapeutic targets for lung cancer by bioinformatics analysis Gene Encoding Chitinase 3-Like 1 Protein (CHI3L1) is a Putative Oncogene PTTG promotes invasion in human breast cancer cell line by upregulating EMMPRIN via FAK/Akt/mTOR signaling Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells.RNAi-mediated knockdown of pituitary tumor- transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells.PTTG acts as a STAT3 target gene for colorectal cancer cell growth and motility.Pituitary tumor-transforming gene and its binding factor in endocrine cancer.PTTG induces EMT through integrin αVβ3-focal adhesion kinase signaling in lung cancer cells.Securin and separase modulate membrane traffic by affecting endosomal acidification.Gene expression profiles in human HepG2 cells treated with extracts of the Tamarindus indica fruit pulp.Regulation of angiogenesis and invasion by human Pituitary tumor transforming gene (PTTG) through increased expression and secretion of matrix metalloproteinase-2 (MMP-2).Insulin and IGF-1 regulate the expression of the pituitary tumor transforming gene (PTTG) in breast tumor cells.Cell cycle-dependent expression of p42.3 promotes mitotic progression in malignant transformed cells.Low cdc27 and high securin expression predict short survival for breast cancer patients.Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein.Expression and possible role of hPTTG1/securin in cutaneous malignant melanoma.Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation

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Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

http://www.wikidata.org/entity/Q24798304

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Ectopic expression of PTTG1/se ...... n human embryonic kidney cells

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Ectopic expression of PTTG1/se ...... n human embryonic kidney cells

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Ectopic expression of PTTG1/se ...... n human embryonic kidney cells

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Ectopic expression of PTTG1/se ...... n human embryonic kidney cells

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Mohammed T Malik

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Sham S Kakar

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Tariq Hamid

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P2860

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

PTTG/securin activates expression of p53 and modulates its function

Molecular cloning and characterization of the tumor transforming gene (TUTR1): a novel gene in human tumorigenesis

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

Creation of human tumour cells with defined genetic elements

Human pituitary tumor-transforming gene induces angiogenesis

Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

Assignment of the human tumor transforming gene TUTR1 to chromosome band 5q35.1 by fluorescence in situ hybridization

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

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