Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
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The emerging role of pituitary tumor transforming gene in tumorigenesisCornelia de Lange syndrome, cohesin, and beyondHuman securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinasePTTG/securin activates expression of p53 and modulates its functionEctopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cellsThe influence of the pituitary tumor transforming gene-1 (PTTG-1) on survival of patients with small cell lung cancer and non-small cell lung cancer.Pituitary adenomas: historical perspective, surgical management and future directionsTranscriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade.Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosisPTTG1 inhibits SMAD3 in prostate cancer cells to promote their proliferationPTTG1 attenuates drug-induced cellular senescenceActivation of mitogen-activated protein kinase cascade regulates pituitary tumor-transforming gene transactivation function.Critical differences between isoforms of securin reveal mechanisms of separase regulationEffect of PTTG on endogenous gene expression in HEK 293 cells.Pituitary tumor-transforming gene expression is a prognostic marker for tumor recurrence in squamous cell carcinoma of the head and neck.Methylation alterations are not a major cause of PTTG1 misregulation.Mechanisms for pituitary tumorigenesis: the plastic pituitary.Mir-655 up-regulation suppresses cell invasion by targeting pituitary tumor-transforming gene-1 in esophageal squamous cell carcinoma.Gene expression profiling of breast cancers with emphasis of beta-catenin regulationPituitary tumor transforming gene-1 haplotypes and risk of pituitary adenoma: a case-control study.Potential of gene therapy for the treatment of pituitary tumorsOverexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts.Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.Functional role of estrogen in pituitary tumor pathogenesis.Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation.The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature.Correlations of pituitary tumor transforming gene expression with human pituitary adenomas: a meta-analysis.Oncogenes in thyroid cancer.Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin.Evidence for cooperative transforming activity of the human pituitary tumor transforming gene and human T-cell leukemia virus type 1 Tax.Cloning of Porcine Pituitary Tumor Transforming Gene 1 and Its Expression in Porcine Oocytes and EmbryosPTTG1 oncogene promotes tumor malignancy via epithelial to mesenchymal transition and expansion of cancer stem cell populationOverexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signallingPTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma.Expression of pituitary tumor transforming gene in human gastric carcinomaGene expression profiling analysis of MENX-associated rat pituitary adenomas contributes to understand molecular mechanisms of human pituitary adenomas.Novel functions of thyroid hormone receptor mutants: beyond nucleus-initiated transcription.Proliferation marker securin identifies favourable outcome in invasive ductal breast cancer.Rat prolactinoma cell growth regulation by epidermal growth factor receptor ligands
P2860
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P2860
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@ast
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@en
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@nl
type
label
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@ast
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@en
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@nl
prefLabel
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@ast
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@en
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@nl
P2093
P3181
P1476
Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)
@en
P2093
A Valentini
G A Horwitz
M D Bronstein
M Nakashima
T R Prezant
P304
P3181
P356
10.1210/ME.13.1.156
10.1210/MEND.13.1.0225
P407
P577
1999-01-01T00:00:00Z