GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.
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50 years of hurdles and hope in anxiolytic drug discoveryDifferential regulation of the postsynaptic clustering of γ-aminobutyric acid type A (GABAA) receptors by collybistin isoforms.The age of anxiety: role of animal models of anxiolytic action in drug discovery.Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.The clinical implications of mouse models of enhanced anxiety.Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus.Neurobiology of memory and anxiety: from genes to behavior.The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in childrenThe intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit.Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptorsTiagabine in anxiety disorders.Gephyrin clustering is required for the stability of GABAergic synapses.Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity.Gephyrin expression and clustering affects the size of glutamatergic synaptic contacts.Two pools of Triton X-100-insoluble GABA(A) receptors are present in the brain, one associated to lipid rafts and another one to the post-synaptic GABAergic complex.The behavioral pharmacology of zolpidem: evidence for the functional significance of α1-containing GABA(A) receptors.Association of oxidative stress to the genesis of anxiety: implications for possible therapeutic interventionsNeurobiological mechanisms of stress resilience and implications for the aged population.Investigation of ethanol-induced impairment of spatial memory in gamma2 heterozygous knockout mice.Experimental models for anxiolytic drug discovery in the era of omes and omics.Oxidative stress is the new stress.Effects of prenatal stress on anxiety-like behavior and nociceptive response in rats.Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.Association study of GABRG2 polymorphisms with suicidal behaviour in schizophrenia patients with alcohol use disorder.Inhibition in the amygdala anxiety circuitry.γ2 GABAR Trafficking and the Consequences of Human Genetic Variation
P2860
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P2860
GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
GABAA receptor gamma 2 subunit ...... ic response to benzodiazepines
@nl
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@ast
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@en
type
label
GABAA receptor gamma 2 subunit ...... ic response to benzodiazepines
@nl
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@ast
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@en
prefLabel
GABAA receptor gamma 2 subunit ...... ic response to benzodiazepines
@nl
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@ast
GABAA receptor gamma 2 subunit ...... c response to benzodiazepines.
@en
P2093
P2860
P356
P1433
P1476
GABAA receptor gamma 2 subunit ...... ic response to benzodiazepines
@en
P2093
Angel L De Blas
Celia P Miralles
Dev Chandra
Esa R Korpi
P2860
P2888
P356
10.1186/1471-2202-6-30
P407
P577
2005-04-25T00:00:00Z
P5875
P6179
1016072540