Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs - Wikidata - awgldk - TriplyDB

Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs

Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs

http://www.wikidata.org/entity/Q24805221

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Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution Ubiquitin-Mediated Degradation of Aurora Kinases Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly Targeting the Mitotic Catastrophe Signaling Pathway in Cancer Functions of Aurora kinase C in meiosis and cancer Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review Aurora kinase A in gastrointestinal cancers: time to target Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos Aurora-A kinase is essential for bipolar spindle formation and early development Cdk1, Plks, Auroras, and Neks: the mitotic bodyguards Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.Dictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases.SERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery tool Danusertib, an aurora kinase inhibitor.Evolutionary reconstruction and population genetics analysis of aurora kinases.Aurora kinases: shining lights on the therapeutic horizon?Aurora A and B kinases as targets for cancer: will they be selective for tumors?Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).Mitosis-targeted anti-cancer therapies: where they stand.Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery The chromosomal basis of meiotic acentrosomal spindle assembly and function in oocytes.Mechanisms for nonmitotic activation of Aurora-A at cilia.Specialize and Divide (Twice): Functions of Three Aurora Kinase Homologs in Mammalian Oocyte Meiotic Maturation.Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells.Aurora kinase targeted therapeutics in oncology: past, present and future.Regulation of AURKC expression by CpG island methylation in human cancer cells.An essential Aurora-related kinase transiently associates with spindle pole bodies during Plasmodium falciparum erythrocytic schizogony Long residence times revealed by Aurora A kinase-targeting fluorescent probes derived from inhibitors MLN8237 and VX-689.Differential Selective Pressures Experienced by the Aurora Kinase Gene Family.A role for Aurora C in the chromosomal passenger complex during human preimplantation embryo development.Non-small-cell lung cancer pathological subtype-related gene selection and bioinformatics analysis based on gene expression profiles.The functional diversity of Aurora kinases: a comprehensive review

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Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs

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P2860

The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

MrBayes 3: Bayesian phylogenetic inference under mixed models

Crystal structure of aurora-2, an oncogenic serine/threonine kinase

MRBAYES: Bayesian inference of phylogenetic trees

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

TreeView: an application to display phylogenetic trees on personal computers

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