Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studiesCarbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studiesCarbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitorsCarbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adductCarbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library.Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates.Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of hypoxiCarbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides.Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.Carbonic anhydrases as targets for medicinal chemistry.Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide.Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives.Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives.Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors.Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase.Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.
P921
Q27645104-DED04E44-7AE2-44BA-9CFC-F3C9AC094CC6Q27646370-B6A51791-8DB9-430E-AB2F-AB12F4575EEEQ27650131-07D6600A-0614-45E6-AA05-2CEFB3D5B440Q27650185-1003B6A6-6270-4041-8B8C-4AFE7DB0275CQ31117158-98681FBF-8DCF-4179-A964-0F4104811AE0Q31117406-878B648B-EDE1-4EDC-BCED-97E467BF9752Q31142922-CF598927-4BA8-4876-8244-79D5FB51C88AQ33215399-6AA49463-23A8-4D96-8BD7-B2B43F4E87F3Q33215545-BF345E2D-CCDA-424F-8C4D-2C6DF8B8C53FQ33223506-F92F61CD-CF4B-41F3-B730-93876E7C8897Q33227647-DA68B254-9CB7-4AE8-A11E-6557DCE2BDB0Q33233118-4AAE7A4C-D004-41C5-9BB8-E2C80E13C26FQ33236577-1EFD5558-4BF2-445F-BFFF-C569BE326F5FQ33266035-524EE735-10FA-48B7-850B-0B5A098332F6Q33297979-795AC9BE-03C9-4C41-A212-089E3F526FADQ33321654-7B20C1A2-FC5E-40DA-BC5F-9E4BE3590427Q34390219-66A25FEC-CD13-452D-8496-9737725FC0E4Q36809436-1055D2FA-8715-418F-B3FC-E884E2A0CA5BQ40395525-26D1A4E9-E88F-4503-B8B4-B0052384FC97Q42191650-DC31A51F-CF50-4063-9241-0D2976222FACQ42199783-9C1C4BC6-C7C9-4576-8918-AE340C590903Q43925029-51FC326C-3D54-4A27-BF0C-71D53CE43F18Q44011757-5B0C480B-8241-40E1-9A5C-9816CFD0AC28Q44345444-A8DC2944-9311-4481-BDA3-7C9BBA33B025Q44345451-88C9E7C4-0A73-44BF-8EDD-833248575085Q44366527-31190D47-1CD3-469C-8FB2-B74AE471777CQ44441546-043B4EFE-F7A3-4DC1-8CBF-8773F7AA44C6Q44441549-92CD858F-20B5-44FA-98BA-36B28C075F9EQ44651592-6A9EF0DB-CA3B-4D00-933C-8F636A357039Q44670158-730BF5DC-BA69-4966-B9B6-5BE380B72C52Q44698665-DF826F97-4628-4A53-A100-296EABF59E5DQ44769397-CD3940BC-ECEB-42C9-AF1E-EE82254AC28AQ44841735-EF850D74-770C-43AC-B931-7DCCA62E6710Q44893597-F549F63B-1D77-45DF-B6A4-3BAFB709FCDEQ44900722-B746E6A1-9B3C-49E8-B1BA-04529C19669BQ45121223-94D25968-7C7F-469B-89F7-9746504A5E21Q45152477-E90B6CF8-D451-455D-8837-6771DA9B8554Q45190009-A78412AD-9034-4946-B463-9A09374279D1Q45248232-3BF1B3A5-0A6D-4BDE-8023-80C5A905C18BQ45248304-A8C0B757-92D3-429D-9095-F53783F26DE4
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Ethoxzolamide
@vi
Etokszolamid
@bs
Etokszolamid
@sh
Etokszolamid
@sr
ethoxzolamide
@en
type
label
Ethoxzolamide
@vi
Etokszolamid
@bs
Etokszolamid
@sh
Etokszolamid
@sr
ethoxzolamide
@en
altLabel
6-Ethoxy-1,3-benzothiazole-2-sulfonamide
@en
6-ethoxy-2-benzothiazolesulfonamide
@en
6-ethoxybenzothiazole-2-sulfonamide
@en
Cardrase®
@en
ETHOXZOLAMIDE
@en
Ethamide®
@en
Ethoxazolamide
@en
Ethoxyzolamide
@en
Ethoxzolamide
@en
ethoxazolamide
@en
prefLabel
Ethoxzolamide
@vi
Etokszolamid
@bs
Etokszolamid
@sh
Etokszolamid
@sr
ethoxzolamide
@en
P129
P638
P672
P486
P592
P6366
P661
P662
P665
P6694
P683
P2067
P231
P232
P233
CCOC1=CC2=C(C=C1)N=C(S2)S(=O)(=O)N
P234
1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)
P235
OUZWUKMCLIBBOG-UHFFFAOYSA-N
P2566
100.006.546