Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.
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Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigationsDithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in VivoThe anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studiesA class of carbonic anhydrase I - selective activators.Topiramate hyperpolarizes and modulates the slow poststimulus AHP of rat olfactory cortical neurones in vitro.A perspective on quantitative structure-activity relationships and carbonic anhydrase inhibitors.Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.Molecular pharmacodynamics, clinical therapeutics, and pharmacokinetics of topiramate.Carbonic anhydrase inhibition as a cancer therapy: a review of patent literature, 2007 - 2009.Anticonvulsant/antiepileptic carbonic anhydrase inhibitors: a patent review.Antiobesity carbonic anhydrase inhibitors: a literature and patent review.How many carbonic anhydrase inhibition mechanisms exist?Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors.Carbonic anhydrase inhibition and the management of neuropathic pain.Antioxidant activity of topiramate: an antiepileptic agent.Measurement of nanomolar dissociation constants by titration calorimetry and thermal shift assay - radicicol binding to Hsp90 and ethoxzolamide binding to CAIIHydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors.Topiramate modulates pH of hippocampal CA3 neurons by combined effects on carbonic anhydrase and Cl-/HCO3- exchange.The sulfamide motif in the design of enzyme inhibitors.Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies.Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors.Serendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases.Quantitative structure-activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors.Regulation of high glucose-induced apoptosis of brain pericytes by mitochondrial CA VA: A specific target for prevention of diabetic cerebrovascular pathology.Weight regain after discontinuation of topiramate treatment in patients with migraine: a prospective observational study.A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents.Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.Crystallography and Its Impact on Carbonic Anhydrase ResearchModulation of carbonic anhydrase activity and its applications in therapyTherapeutic applications of sulfamates
P2860
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P2860
Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@en
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@nl
type
label
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@en
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@nl
prefLabel
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@en
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@nl
P2093
P1476
Carbonic anhydrase inhibitors: ...... es with isozymes I, II and IV.
@en
P2093
Claudiu T Supuran
Francesco Abbate
Harald Waldeck
Jochen Antel
Samuel David
Siegfried Schäfer
P304
P356
10.1016/S0960-894X(03)00029-5
P407
P577
2003-03-01T00:00:00Z