Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum partheniumComparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver.Microtubule-interfering activity of parthenolideParthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells.Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell linesParthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.Modulation of DNA methylation by a sesquiterpene lactone parthenolide.Parthenolide: from plant shoots to cancer roots.Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells.Parthenolide enhances dacarbazine activity against melanoma cells.Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation.Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells.Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest.Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kappaB.Sesquiterpene lactone parthenolide, an inhibitor of IkappaB kinase complex and nuclear factor-kappaB, exerts beneficial effects in myocardial reperfusion injury.Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.Parthenolide reduces cell proliferation and prostaglandin E2 [corrected] in human endometriotic stromal cells and inhibits development of endometriosis in the murine model.Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells.Parthenolide and its photochemically synthesized 1(10)Z isomer: chemical reactivity and structure-activity relationship studies in human leucocyte chemotaxis.Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia.Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis.The lipophilic hapten parthenolide induces interferon-gamma and interleukin-13 production by peripheral blood-derived CD8+ T cells from contact allergic subjects in vitro.Parthenolide from Parthenium integrifolium reduces tumor burden and alleviate cachexia symptoms in the murine CT-26 model of colorectal carcinoma.Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity
P921
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P921
description
chemesch Verbindung
@lb
chemical compound
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chemical compound
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chemical compound
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chemická sloučenina
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chemická zlúčenina
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chemiese verbinding
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chemische Verbindung
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chemische Verbindung
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chemische verbinding
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name
Partenolid
@sh
Partenolid
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Partenolide
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Parthenolide
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Parthenolide
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Parthenolide
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Parthénolide
@fr
Партенолид
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پارتنولید
@azb
پارتنولید
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type
label
Partenolid
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Partenolid
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Partenolide
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Parthenolide
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Parthenolide
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Parthenolide
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Parthénolide
@fr
Партенолид
@ru
پارتنولید
@azb
پارتنولید
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altLabel
C15H20O3
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prefLabel
Partenolid
@sh
Partenolid
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Partenolide
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Parthenolide
@en
Parthenolide
@nl
Parthenolide
@vi
Parthénolide
@fr
Партенолид
@ru
پارتنولید
@azb
پارتنولید
@fa
P486
P592
P6366
P646
P661
P662
P665
P683
P1579
P2017
C/C/1=C/CCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C
P2064
P2067
248.141245
P2085
P231
20554-84-1