Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Design of a Type-1 Diabetes Vaccine Candidate Using Edible Plants Expressing a Major Autoantigen.

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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2016 nî lūn-bûn

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2016 թուականին հրատարակուած գիտական յօդուած

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2016 թվականին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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type

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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P1476

Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

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P2093

François-Xavier Mauvais

http://www.w3.org/2001/XMLSchema#string

Julien Diana

http://www.w3.org/2001/XMLSchema#string

Peter van Endert

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P2860

Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy.

Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.

Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell-associated epitopes using combinatorial MHC multimers.

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.

Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope

Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

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scholarly article

review article

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2133334

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10.12688/F1000RESEARCH.7411.1

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English

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Peter M van Endert

Julien Diana

François-Xavier Mauvais

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2016-04-22T00:00:00Z

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301598985

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27158463

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type-1 diabetes

pathogenesis

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4847563

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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

about

P2860

P2860

Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P3181

P356

P407

P478

P50

P577

P5875

P698

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P3181

P356

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P1476

P2093

P2860

P304

P31

P3181

P356

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P478

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P932