Novel amidines and analogues as promising agents against intracellular parasites: a systematic review
about
The discovery of a novel antibiotic for the treatment of Clostridium difficile infections: a story of an effective academic–industrial partnership4-Aminopyridyl-Based CYP51 Inhibitors as Anti- Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo PotencySoulamarin isolated from Calophyllum brasiliense (Clusiaceae) induces plasma membrane permeabilization of Trypanosoma cruzi and mytochondrial dysfunctionAn Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection.In vitro and in vivo studies of the biological activity of novel arylimidamides against Trypanosoma cruziIn vitro and in vivo biological effects of novel arylimidamide derivatives against Trypanosoma cruzi.Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor ImatinibVaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in MiceDifferent Therapeutic Outcomes of Benznidazole and VNI Treatments in Different Genders in Mouse Experimental Models of Trypanosoma cruzi Infection.In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi.Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi.Design or screening of drugs for the treatment of Chagas disease: what shows the most promise?Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Prophylactic and therapeutic DNA vaccines against Chagas disease.Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models.Drug target identification in protozoan parasites.Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.Ginseng Stem-and-Leaf Saponin (GSLS)-Enhanced Protective Immune Responses Induced by Toxoplasma gondii Heat Shocked Protein 70 (HSP70) Against Toxoplasmosis in Mice.Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents.Hydroxamic acid derivatives: a promising scaffold for rational compound optimization in Chagas disease.Structure-dependent binding of arylimidamides to the DNA minor groove.Experimental and Clinical Treatment of Chagas Disease: A Review.DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-Indole Antibiotics.Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus Via N-Terminal Guanidinium Substitution.The Trypanocidal Effect of Novel Quinolines: In vitro And In vivo Studies.Pharmacological inhibition of the transcription factor PU.1 in leukemia.In vitro, in silico and in vivo analysis of novel aromatic amidines against Trypanosoma cruzi.DFT and TDDFT investigation of the Schiff base formed by tacrine and saccharin.Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates.
P2860
Q26767471-FA8BA50B-3702-4F71-8B27-E6DA01544576Q27684956-1DEB92C6-CC0E-4286-BA9F-55CB2F3072AEQ28536088-45E3B21C-F486-4690-AB6E-5E5403B1F524Q30359632-F5798378-1151-4AFA-B3E7-D0277915FC38Q33553551-03BAD010-5122-44E4-A274-ECE5150B5067Q33798362-D666D9C4-737B-457C-A8BF-F8C9D148FB4EQ33798498-255096EC-E44A-41FD-984E-D78FA90E5FECQ34705820-CB8E109D-CEFE-48CB-8E23-F02E175706C1Q35843444-7398C23A-1AA8-40B2-AAB3-43CB711D492BQ36290550-1A94CA77-97D6-415B-9813-ABF1E46D0BFCQ36730126-630B0716-BE3E-4B7B-A495-DC7855CAB5F1Q37120187-9B004208-B73B-4CCA-A50F-9560621D37FDQ37401820-CB741586-58CB-4896-A789-B7F0B1C0DCB5Q38261264-CEB0FC48-F9FE-41CD-9A35-DEA730FBA26FQ38426148-7DC599B6-0874-46A5-93CB-4F487D5A898DQ38655231-4E5B1376-AF47-4A2A-AAAD-ED30CC80D56AQ38847814-FCFEF6B7-9250-4B03-8DD2-ECF17333339EQ38910567-C94A44EC-EBC6-4A6E-B35D-DA5FB56D337DQ39201614-23EEB6D0-9CE3-4E58-A3D3-B90BF1A377CBQ39552904-4E2A34E3-5EF9-4054-A381-5EB08FA996E1Q41022118-6EA09DD1-588F-46D4-A43F-40F5CFF9F168Q41910359-9F1B7D5A-1C28-4790-8BF2-00563A3FE0F9Q41989175-9A41C4D2-E61E-44BA-9B69-E97701B61AA2Q42364863-30CC2244-FEBD-4597-8A42-0B693388AC29Q42737373-E01F0D5A-5BFF-48DB-97BA-D1AC76492E00Q46248416-DEF27A9A-B2CB-4D7C-9634-0E5F44D9C5D0Q46873766-06220403-578C-4853-B5C5-C0D15F450896Q47371103-46534E44-556E-4DFE-9234-592EE63FD15CQ50981651-19812D1F-F186-4887-B813-5E36BEB050B1Q53065224-FD405586-3C40-4751-B58E-C8BFCF515D65
P2860
Novel amidines and analogues as promising agents against intracellular parasites: a systematic review
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Novel amidines and analogues a ...... parasites: a systematic review
@ast
Novel amidines and analogues a ...... parasites: a systematic review
@en
Novel amidines and analogues a ...... parasites: a systematic review
@nl
type
label
Novel amidines and analogues a ...... parasites: a systematic review
@ast
Novel amidines and analogues a ...... parasites: a systematic review
@en
Novel amidines and analogues a ...... parasites: a systematic review
@nl
prefLabel
Novel amidines and analogues a ...... parasites: a systematic review
@ast
Novel amidines and analogues a ...... parasites: a systematic review
@en
Novel amidines and analogues a ...... parasites: a systematic review
@nl
P2093
P2860
P3181
P1433
P1476
Novel amidines and analogues a ...... parasites: a systematic review
@en
P2093
A Hemphill
D W Boykin
K Werbovetz
M N C Soeiro
P2860
P304
P3181
P356
10.1017/S0031182013000292
P407
P577
2013-04-08T00:00:00Z