Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove
about
Novel amidines and analogues as promising agents against intracellular parasites: a systematic reviewSmall-molecule Binding to the DNA Minor Groove Is Mediated by a Conserved Water ClusterCharacterization of a novel DNA minor-groove complex.Binding-linked protonation of a DNA minor-groove agentSequence-specific minor groove binding by bis-benzimidazoles: water molecules in ligand recognition.Analogs of pentamidine as potential anti-Pneumocystis chemotherapeutics.Aromatic diamidines as antiparasitic agents.Antiparasitic compounds that target DNA.Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound waterA role for water molecules in DNA-ligand minor groove recognitionDesign of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif.Water-mediated binding of agents that target the DNA minor groove.Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues.Polyamide curvature and DNA sequence selective recognition: use of 4-aminobenzamide to adjust curvature.Molecular dynamics of water-mediated interactions of a linear benzimidazole-biphenyl diamidine with the DNA minor groove.Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents.Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum.Unusually strong positive cooperativity in binding of peptides to latent membrane protein-1 DNA fragments of the Epstein-Barr viral gene.The Role of the DNA Backbone in Minor-Groove Ligand Binding.A difunctional squarylium indocyanine dye distinguishes dead cells through diverse staining of the cell nuclei/membranes.
P2860
Q26825025-61641A8E-271B-4754-9924-33A9BDDAAA70Q27675672-2E1EC1E1-DE20-41BC-8D67-D4E21B199D92Q34184633-4427D82A-1738-4699-B555-7032A32FA7C5Q34354149-B0981A5B-4360-4E78-8279-D5E727FB77F1Q34759701-66EA0541-0F43-41D0-9CC9-8634EEF73FAEQ35740410-CF376AA4-F0E8-487C-9797-7675F26DC47AQ36210897-60EB5D58-334A-444A-9D20-52276EC00FDAQ36835020-DF79778B-7325-4872-BC28-E58F2C0A66D2Q36844141-0A7EAB75-A42A-4053-9AE9-073313C90117Q37157891-692501FF-614D-46BC-B2C5-664D4C7A186FQ37397976-0FA78394-30A2-4A08-B034-83B7F7381E50Q38280615-23491034-CFC3-4FAE-A516-F5F4917A0D8BQ39099156-E07A211C-48CC-4088-A0B1-AAC1A4D8461CQ40080506-58907E2C-3564-4107-A1FC-FD0237CE9437Q41385158-19145EAB-D6A2-4F90-8E1E-D0B5A53A2D59Q42924281-D06C5E84-AD40-46CC-9462-6C2CC33BE173Q42927937-F348E112-2AA2-4B52-9996-32A8DD9AF9E1Q43594376-F956C6E3-D024-4477-843A-A8278C393581Q48062497-4B88B163-BB92-4476-BBDB-42891405C5AFQ52761242-81C115E9-F6E7-4BD5-A768-8D7CD5CA09F9
P2860
Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Strong binding in the DNA mino ...... ch the curvature of the groove
@ast
Strong binding in the DNA mino ...... ch the curvature of the groove
@en
Strong binding in the DNA mino ...... ch the curvature of the groove
@nl
type
label
Strong binding in the DNA mino ...... ch the curvature of the groove
@ast
Strong binding in the DNA mino ...... ch the curvature of the groove
@en
Strong binding in the DNA mino ...... ch the curvature of the groove
@nl
prefLabel
Strong binding in the DNA mino ...... ch the curvature of the groove
@ast
Strong binding in the DNA mino ...... ch the curvature of the groove
@en
Strong binding in the DNA mino ...... ch the curvature of the groove
@nl
P2093
P356
P1476
Strong binding in the DNA mino ...... ch the curvature of the groove
@en
P2093
Alexandra Joubert
Binh Nguyen
Christian Bailly
Donald Hamelberg
Michael P H Lee
W David Wilson
P304
P356
10.1021/JA027953C
P407
P577
2002-11-20T00:00:00Z