Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
about
Structure of the human glucagon class B G-protein-coupled receptorLandmark studies on the glucagon subfamily of GPCRs: from small molecule modulators to a crystal structureGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsConformational states of the full-length glucagon receptorThe Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased AgonismKey interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptorGlucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domainGenetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCRGeneration of a highly diverse panel of antagonistic chicken monoclonal antibodies against the GIP receptorGpr125 modulates Dishevelled distribution and planar cell polarity signaling.Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptorRearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptorsInsights into the structure of class B GPCRs.Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus.The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanismInternational Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment AnalysisThe VPAC1 receptor: structure and function of a class B GPCR prototype.Predicted structure of agonist-bound glucagon-like peptide 1 receptor, a class B G protein-coupled receptorUse of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled ReceptorsStructure of Class B GPCRs: new horizons for drug discovery.Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.Genetically encoding new bioreactivity.Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.Production and evaluation of parathyroid hormone receptor1 ligands with intrinsic or assembled peroxidase domains.A new era for GPCR research: structures, biology and drug discovery.Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor.
P2860
Q24601619-625F9AF2-6732-407B-A497-1ADF4683C365Q26798049-B77DAC7C-92CF-4025-A4E1-BED577ABB5AFQ28067465-961B8FC6-966A-4531-A186-58973EADC517Q28082755-E152F641-A6F5-4FFD-84A5-C386B3300EBCQ28265667-31A297F6-7B09-4108-B816-6AF171249770Q28276469-2A9D556D-8800-48A3-AA8A-A04150F533B3Q28278129-93C05C09-6CD4-4BE2-9EA3-A399AB3575E7Q28542687-BE333C74-63E9-450E-8AFB-25EF953FC228Q28572982-C9DEE09D-A12D-469C-9E3D-7C86C3E3A1E2Q30358836-6A1C8D57-54C6-493D-B8D0-3EB1ACD43A27Q30541107-2E5DEDA9-756F-4B31-BDA6-FAF7BC813C5DQ33615669-F4D5811C-F1F2-4A00-898C-1C7464AF0BAEQ33793135-1B7D6B07-1760-4887-8DE5-851FE359C876Q33806122-8DF567E8-1A7E-4B06-8FF9-C5C138F0F1FCQ34393487-8E2A51D1-1D5F-4ACA-867F-E5EDFDDF68ADQ34913473-BAA1BFCA-EA7F-4CE3-8FF0-F392AFC59981Q35159111-FA1490C7-3477-4A4A-85EF-6D6755856B5FQ35383816-1A73BA49-C1DC-40F6-8559-86B7AAF4B132Q35943313-A99ED667-8620-44B5-8F38-216ADDD167ABQ36403782-5EDF71FA-8AE2-4F91-8363-8E7712129030Q36471233-B18AD371-9E70-4423-A3B5-8F89AAA0D000Q36650346-65EF0A38-FF7C-40BD-AA52-743A617857AEQ37098923-44ACE22C-47A1-42DC-8882-CCA35776935DQ38195892-904DC2F9-DF61-479E-96A8-5A06D229ACFFQ38644545-CE99698C-5399-44A2-BB16-32FB814A4A27Q38976621-C807C282-72AB-4FA1-80AB-21EFE1A19016Q41598194-8CB47B9E-57F4-4EF9-8E10-556D14576AC6Q42376140-E70CE441-0790-48D4-B925-D42BD3EECBBEQ42723972-25F755A0-0E48-407D-9E76-B4918FF87A5FQ53439320-F2705888-E06A-4842-AEC4-C6675D510A06
P2860
Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structure and mechanism for re ...... B G-protein-coupled receptors
@ast
Structure and mechanism for re ...... B G-protein-coupled receptors
@en
Structure and mechanism for re ...... B G-protein-coupled receptors
@nl
type
label
Structure and mechanism for re ...... B G-protein-coupled receptors
@ast
Structure and mechanism for re ...... B G-protein-coupled receptors
@en
Structure and mechanism for re ...... B G-protein-coupled receptors
@nl
prefLabel
Structure and mechanism for re ...... B G-protein-coupled receptors
@ast
Structure and mechanism for re ...... B G-protein-coupled receptors
@en
Structure and mechanism for re ...... B G-protein-coupled receptors
@nl
P2860
P3181
P356
P1476
Structure and mechanism for re ...... B G-protein-coupled receptors
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/APS.2011.170
P407
P577
2012-01-23T00:00:00Z
P5875
P6179
1030754372