Conformational states of the full-length glucagon receptor - Wikidata - awgldk - TriplyDB

Conformational states of the full-length glucagon receptor

Conformational states of the full-length glucagon receptor

http://www.wikidata.org/entity/Q28265667

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A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R)Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles Structure of the full-length glucagon class B G-protein-coupled receptor.Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors Nanobodies to Study G Protein-Coupled Receptor Structure and Function.Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs.Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domain.Structural basis of ligand interaction with atypical chemokine receptor 3.Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.Activation and conformational dynamics of a class B G-protein-coupled glucagon receptor.Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer.7TM Domain Structure of Adhesion GPCRs.The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling.Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR.Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y1 Receptor.Structure of the glucagon receptor in complex with a glucagon analogue.Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1.Crystal structure of the GLP-1 receptor bound to a peptide agonist.Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell.Solution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity.Molecular Modeling of Structures and Interaction of Human Corticotropin-Releasing Factor (CRF) Binding Protein and CRF Type-2 Receptor.GPCRM: a homology modeling web service with triple membrane-fitted quality assessment of GPCR models.

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Conformational states of the full-length glucagon receptor

http://www.wikidata.org/entity/Q28265667

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2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Conformational states of the full-length glucagon receptor

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Nature Communications

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Conformational states of the full-length glucagon receptor

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Beili Wu

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Bruce D Pascal

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Chong Wang

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Clinton S Potter

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Dehua Yang

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Fai Y Siu

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Gaojie Song

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Graham M West

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Hu Zhou

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Huaiyu Yang

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Conformation of a peptide ligand bound to its G-protein coupled receptor

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS

Structure of class B GPCR corticotropin-releasing factor receptor 1

Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1

Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

Structure of the human glucagon class B G-protein-coupled receptor

Molecular basis for negative regulation of the glucagon receptor

Structural basis of Wnt recognition by Frizzled

Structure and mechanism for recognition of peptide hormones by Class B G-protein-coupled receptors

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1502140

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10.1038/NCOMMS8859

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6

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Bridget Carragher

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