RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis - Wikidata - awgldk - TriplyDB

RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

http://www.wikidata.org/entity/Q26853207

about

Threshold-controlled ubiquitination of the EGFR directs receptor fate Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway HECT and RING finger families of E3 ubiquitin ligases at a glance STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1 Biological influence of Hakai in cancer: a 10-year review Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads When ubiquitin meets NF-κB: a trove for anti-cancer drug development RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination NIRF/UHRF2 occupies a central position in the cell cycle network and allows coupling with the epigenetic landscape Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases Targeting the ubiquitin pathway for cancer treatment Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis OLA1 in centrosome biology alongside the BRCA1/BARD1 complex: looking beyond centrosomes Regulation of ERBB3/HER3 signaling in cancer Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases Ubiquitination-induced fluorescence complementation (UiFC) for detection of K48 ubiquitin chains in vitro and in live cells Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors BMP signaling controls muscle mass Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration.Comparison of splenic transcriptome activity of two rainbow trout strains differing in robustness under regional aquaculture conditions.Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells.USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses Degradation of the transcription factor Twist, an oncoprotein that promotes cancer metastasis.Cellular senescence and protein degradation: breaking down cancer E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Arsenite binds to the RING finger domains of RNF20-RNF40 histone E3 ubiquitin ligase and inhibits DNA double-strand break repair.Limiting the power of p53 through the ubiquitin proteasome pathway.Domain organization of XAF1 and the identification and characterization of XIAP(RING) -binding domain of XAF1.The ubiquitin ligase Nedd4-1 participates in denervation-induced skeletal muscle atrophy in mice.Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5.Multi-analyte network markers for tumor prognosis.Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.Versatile roles of k63-linked ubiquitin chains in trafficking.

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RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

http://www.wikidata.org/entity/Q26853207

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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type

label

RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

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Nature Reviews Cancer

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RINGs of good and evil: RING f ...... ur suppression and oncogenesis

@en

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Allan M. Weissman

http://www.w3.org/2001/XMLSchema#string

Stanley Lipkowitz

http://www.w3.org/2001/XMLSchema#string

P2860

Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Hallmarks of Cancer: The Next Generation

Identification of a cryptic nucleolar-localization signal in MDM2

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways

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629-43

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scholarly article

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1116352

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10.1038/NRC3120

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9

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11

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2011-08-24T00:00:00Z

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51591655

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1016268056

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21863050

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3542975

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