Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
about
Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolismNew advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseasesPhosphorylation regulates the ubiquitin-independent degradation of yeast Pah1 phosphatidate phosphatase by the 20S proteasome.Phosphorylation of Yeast Pah1 Phosphatidate Phosphatase by Casein Kinase II Regulates Its Function in Lipid MetabolismYeast Nem1-Spo7 protein phosphatase activity on Pah1 phosphatidate phosphatase is specific for the Pho85-Pho80 protein kinase phosphorylation sites.The phospholipase D superfamily as therapeutic targetsCharacterization of a soluble phosphatidic acid phosphatase in bitter melon (Momordica charantia)Lipin 2 binds phosphatidic acid by the electrostatic hydrogen bond switch mechanism independent of phosphorylation.Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity.LPIN1 deficiency with severe recurrent rhabdomyolysis and persistent elevation of creatine kinase levels due to chromosome 2 maternal isodisomy.Lipin-1 regulates autophagy clearance and intersects with statin drug effects in skeletal muscle.Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.Morphogenesis checkpoint kinase Swe1 is the executor of lipolysis-dependent cell-cycle progressionTORC1 regulates Pah1 phosphatidate phosphatase activity via the Nem1/Spo7 protein phosphatase complexPON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosisLipid partitioning at the nuclear envelope controls membrane biogenesisAltered Lipid Synthesis by Lack of Yeast Pah1 Phosphatidate Phosphatase Reduces Chronological Life Span.Expression of perilipin 5 promotes lipid droplet formation in yeastSignal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emerging Role of Lipin-1.Lipin-1 and lipin-3 together determine adiposity in vivo.Inborn errors of metabolism underlying primary immunodeficiencies.An overview of inborn errors of complex lipid biosynthesis and remodelling.The clinical spectrum of inherited diseases involved in the synthesis and remodeling of complex lipids. A tentative overview.The role of lipin-1 in the pathogenesis of alcoholic fatty liver.Signal transduction in inherited metabolic disorders: a model for a possible pathogenetic mechanism.Membrane defects and genetic redundancy: Are we at a turning point for DYT1 dystonia?Lipin proteins and glycerolipid metabolism: Roles at the ER membrane and beyond.How lipid droplets "TAG" along: Glycerolipid synthetic enzymes and lipid storage.SPRY4-IT1: A novel oncogenic long non-coding RNA in human cancers.Lipin-1 expression is critical for keratinocyte differentiation.Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division.Lipin-1 flexes its muscle in autophagy.The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis.Phospholipase D and Its Essential Role in Cancer.A conserved tryptophan within the WRDPLVDID domain of yeast Pah1 phosphatidate phosphatase is required for its in vivo function in lipid metabolism.The Lipid Droplet and the Endoplasmic Reticulum.LPIN1 promotes epithelial cell transformation and mammary tumourigenesis via enhancing insulin receptor substrate 1 stability.Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis.The mouse liver displays daily rhythms in the metabolism of phospholipids and in the activity of lipid synthesizing enzymes.Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle.
P2860
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P2860
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@ast
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@en
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@nl
type
label
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@ast
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@en
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@nl
prefLabel
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@ast
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@en
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@nl
P2093
P2860
P50
P1476
Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling
@en
P2093
Lauren S Csaki
Loren G Fong
Peter Tontonoz
P2860
P304
P356
10.1016/J.PLIPRES.2013.04.001
P407
P577
2013-04-17T00:00:00Z