Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy. - Wikidata - awgldk - TriplyDB

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.

Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.

http://www.wikidata.org/entity/Q34924245

about

Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism The lipid metabolism gene FTO influences breast cancer cell energy metabolism via the PI3K/AKT signaling pathway.Thyroid states regulate subcellular glucose phosphorylation activity in male mice.Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines TAp73 transcriptionally represses BNIP3 expression.Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation.RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation.Costimulation Endows Immunotherapeutic CD8 T Cells with IL-36 Responsiveness during Aerobic Glycolysis Twist promotes reprogramming of glucose metabolism in breast cancer cells through PI3K/AKT and p53 signaling pathways.Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes.Genetic polymorphisms in glycolytic pathway are associated with the prognosis of patients with early stage non-small cell lung cancer Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism.Impact of Mediterranean diet on metabolic syndrome, cancer and longevity.Metabolic enzymes: key modulators of functionality in cancer stem-like cells.Inhibition of cancer antioxidant defense by natural compounds.The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology.Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1 Autophagy in DNA damage response Everolimus and sirolimus in transplantation-related but different.Metabolic control of signalling pathways and metabolic auto-regulation.GRIM-19: A master regulator of cytokine induced tumor suppression, metastasis and energy metabolism.The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability.PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells.Oncogenic regulation of tumor metabolic reprogramming.Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion.Hexokinases link DJ-1 to the PINK1/parkin pathway.Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity.Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3'-monoxime.Defatting of acetone leaf extract of Acacia karroo (Hayne) enhances its hypoglycaemic potential.Mitophagy as a Protective Mechanism against Myocardial Stress.Exploring Non-Metabolic Functions of Glycolytic Enzymes in Immunity.Hexokinase 2 (HK2), the tumor promoter in glioma, is downregulated by miR-218/Bmi1 pathway.Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease.Signaling and metabolic properties of fast and slow smooth muscle types from mice.

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Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.

http://www.wikidata.org/entity/Q34924245

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@ast

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@en

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@nl

type

label

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@ast

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@en

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@nl

prefLabel

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@ast

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@en

Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@nl

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P1433

Cell Death & Differentiation

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Hexokinase II integrates energ ...... dria and TORCing to autophagy.

@en

P2093

D J Roberts

http://www.w3.org/2001/XMLSchema#string

S Miyamoto

http://www.w3.org/2001/XMLSchema#string

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

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248-257

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scholarly article

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10.1038/CDD.2014.173

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2

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22

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25323588

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4291497

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