The enemy within: endogenous retroelements and autoimmune disease - Wikidata - awgldk - TriplyDB

The enemy within: endogenous retroelements and autoimmune disease

The enemy within: endogenous retroelements and autoimmune disease

http://www.wikidata.org/entity/Q27021785

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Restricting retrotransposons: a review Recent advances in primary Sjogren's syndrome Type I interferonopathies in pediatric rheumatology Human Endogenous Retroviruses as Pathogenic Factors in the Development of Schizophrenia Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family An Ecological Framework of the Human Virome Provides Classification of Current Knowledge and Identifies Areas of Forthcoming Discovery Cause and consequences of the activated type I interferon system in SLE Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production The decline of human endogenous retroviruses: extinction and survival Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)A survey of endogenous retrovirus (ERV) sequences in the vicinity of multiple sclerosis (MS)-associated single nucleotide polymorphisms (SNPs).Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion Regulatory activities of transposable elements: from conflicts to benefits.Mouse knockout models for HIV-1 restriction factors.Aicardi-Goutières syndrome and the type I interferonopathies.Transcriptional activity of human endogenous retroviruses in human peripheral blood mononuclear cells.cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection.Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition Tex19 and Sectm1 concordant molecular phylogenies support co-evolution of both eutherian-specific genes.Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.New bioinformatic tool for quick identification of functionally relevant endogenous retroviral inserts in human genome.The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression.RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity Two case reports of severe myocarditis associated with the initiation of dolutegravir treatment in HIV patients.Adaptation in the innate immune system and heterologous innate immunity.Advances in understanding the role of type I interferons in systemic lupus erythematosus.RNA degradation in antiviral immunity and autoimmunity Human disease phenotypes associated with mutations in TREX1.Innate immunity against HIV-1 infection.Type I interferon dysregulation and neurological disease.The potential role of retroviruses in autoimmunity.Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology.Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production.Immune responses to endogenous retroelements: taking the bad with the good.The role of RNA editing by ADAR1 in prevention of innate immune sensing of self-RNA.Human endogenous retroviruses and cancer.Endogenous Retroelements and the Host Innate Immune Sensors.

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P2860

The enemy within: endogenous retroelements and autoimmune disease

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2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014年の論文

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2014年論文

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2014年論文

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The enemy within: endogenous retroelements and autoimmune disease

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Nature Immunology

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The enemy within: endogenous retroelements and autoimmune disease

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Daniel B Stetson

http://www.w3.org/2001/XMLSchema#string

Hannah E Volkman

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P2860

Initial sequencing and analysis of the human genome

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

Retrotransposons Revisited: The Restraint and Rehabilitation of Parasites

IFI16 is an innate immune sensor for intracellular DNA

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

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415-22

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scholarly article

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10.1038/NI.2872

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