An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
about
Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationExperimental characterization of the human non-sequence-specific nucleic acid interactomeProduction of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodAAPOBEC3 proteins mediate the clearance of foreign DNA from human cellsIFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomesThe NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasomeIRF7: activation, regulation, modification and functionIFI16 is an innate immune sensor for intracellular DNACrystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionActivation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionHerpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNASAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutationsDAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaBRIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediateVaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIVMany stimuli pull the necrotic trigger, an overviewThe inflammasome: in memory of Dr. Jurg TschoppThe helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cellsInnate immune sensing of DNA virusesCytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesionsInflammasomes: too big to missAicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunityInflammation and its role in age-related macular degenerationConverging roles of caspases in inflammasome activation, cell death and innate immunityMycobacterium tuberculosis and the host cell inflammasome: a complex relationshipInterferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localizationDNA vaccines: a simple DNA sensing matter?Molecular mechanisms of inflammasome activation during microbial infectionsRegulation of inflammasome signalingIntracellular nucleic acid sensors and autoimmunityRNA mediated Toll-like receptor stimulation in health and diseaseRecognition of cytosolic DNA by cGAS and other STING-dependent sensorsAn Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to PathologyA clear and present danger: inflammasomes DAMPing down disorders of pregnancyThe enemy within: endogenous retroelements and autoimmune diseaseCrosstalk between Mycobacterium tuberculosis and the host cell
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P2860
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@ast
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en-gb
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@nl
type
label
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@ast
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en-gb
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@nl
prefLabel
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@ast
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en-gb
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
An orthogonal proteomic-genomi ...... NA sensor for the inflammasome
@en
P2093
Christoph Baumann
Evelyn Dixit
Gerhard Dürnberger
Hannah Jahn
Keiryn L Bennett
Melanie Planyavsky
Stephan Blüml
P2860
P304
P3181
P356
10.1038/NI.1702
P407
P577
2009-03-01T00:00:00Z