From sirtuin biology to human diseases: an update - Wikidata - awgldk - TriplyDB

From sirtuin biology to human diseases: an update

From sirtuin biology to human diseases: an update

http://www.wikidata.org/entity/Q27022606

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AROS has a context-dependent effect on SIRT1 Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic health Potential Modulation of Sirtuins by Oxidative Stress Sirtuins, metabolism, and DNA repair Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity Determinants of Sir2-Mediated, Silent Chromatin Cohesion The hallmarks of aging Evidence for a common mechanism of SIRT1 regulation by allosteric activators miR-29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC-1α signaling: Implications for age-related hearing loss Sirtuin Inhibition Induces Apoptosis-like Changes in Platelets and Thrombocytopenia Sirt6 deficiency results in progression of glomerular injury in the kidney A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells SIRT6 is required for normal retinal function Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation.Sirtuin to the rescue: SIRT2 extends life span of BubR1 mice.SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer.SIRT1 in the brain-connections with aging-associated disorders and lifespan Sirtuin 1 is a negative regulator of parathyroid hormone stimulation of matrix metalloproteinase 13 expression in osteoblastic cells: role of sirtuin 1 in the action of PTH on osteoblasts.High expression of Sirt7 served as a predictor of adverse outcome in breast cancer.The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents.Korean Pine Nut Oil Attenuated Hepatic Triacylglycerol Accumulation in High-Fat Diet-Induced Obese Mice.Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human Melanoma Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium.Sirt4: the glutamine gatekeeper.Sirtuin 1 Promotes Hyperoxia-Induced Lung Epithelial Cell Death Independent of NF-E2-Related Factor 2 Activation.Acetylation of Mitochondrial Trifunctional Protein α-Subunit Enhances Its Stability To Promote Fatty Acid Oxidation and Is Decreased in Nonalcoholic Fatty Liver Disease.Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer.Nicotinamide phosphoribosyltransferase in malignancy: a review.Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster.Is SIRT2 required for necroptosis?Sirtuin deacetylases in neurodegenerative diseases of aging.AMP-activated protein kinase as a key molecular link between metabolism and clockwork.Sirtuins in stress response: guardians of the genome.The diversity of histone versus nonhistone sirtuin substrates.Oncogenes and tumor suppressors regulate glutamine metabolism in cancer cells.Intersections between mitochondrial sirtuin signaling and tumor cell metabolism.Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach.Sirtuins and the Metabolic Hurdles in Cancer.SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents.

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P2860

From sirtuin biology to human diseases: an update

http://www.wikidata.org/entity/Q27022606

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2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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From sirtuin biology to human diseases: an update

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JBC.R112.402768

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From sirtuin biology to human diseases: an update

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C. Sebastian

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F. K. Satterstrom

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M. C. Haigis

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R. Mostoslavsky

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P2860

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy

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51

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3522245

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