SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
about
SIRT2 as a Therapeutic Target for Age-Related DisordersSIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylationSIRT2 induces the checkpoint kinase BubR1 to increase lifespanThe histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolismLysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancerThe histone deacetylase SIRT2 stabilizes Myc oncoproteinsInsights into APC/C: from cellular function to diseases and therapeuticsUbiquitin-Mediated Degradation of Aurora KinasesThe controversial world of sirtuinsSirtuins in hematological aging and malignancyInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingMetabolism, longevity and epigeneticsSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismSIRT2, a multi-talented deacetylaseFrom sirtuin biology to human diseases: an updateSirtuins in epigenetic regulationSirtuin-dependent epigenetic regulation in the maintenance of genome integrityParkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1.Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patientsGroup IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.Structure-Based Development of an Affinity Probe for Sirtuin 2Sirtuins in metabolism, DNA repair and cancerThe NAD-dependent deacetylase SIRT2 is required for programmed necrosisSIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stressDosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 functionThe tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylationThe sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migrationSirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosisSir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparumSelective Sirt2 inhibition by ligand-induced rearrangement of the active site.Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD(+)-dependent deacetylasesRejuvenating sirtuins: the rise of a new family of cancer drug targetsCdc20: a potential novel therapeutic target for cancer treatmentFunctional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection.Sirtuin 2 Regulates Microvascular Inflammation during Sepsis.Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer.Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma.Emerging role of sirtuins on tumorigenesis: possible link between aging and cancerEssential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.
P2860
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P2860
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@ast
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en-gb
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@nl
type
label
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@ast
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en-gb
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@nl
prefLabel
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@ast
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en-gb
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@nl
P2093
P2860
P921
P3181
P1433
P1476
SIRT2 maintains genome integri ...... ough regulating APC/C activity
@en
P2093
Athanassios Vassilopoulos
Chu-Xia Deng
Cuiling Li
David Gius
Hongtao Yu
Hyun-Seok Kim
Junfang Ji
Rui-Hong Wang
Seong-Hoon Park
P2860
P304
P3181
P356
10.1016/J.CCR.2011.09.004
P407
P577
2011-10-18T00:00:00Z